Technology Offerings

Novel Steroid Compounds Show Promise Against Malaria

A series of novel low molecular weight compounds with high activity against Plasmodium falciparum have been developed, synthesized and tested. The compounds are based on a substituted steroidal pharmacophor and are as antiinfective agents in their structure completely new.
The compounds are highly active against red blood cell stages of P. falciparum, also of chloroquine-resistant parasites. Present SAR data indicate that the hydrophobic steroid component and a hydroxyarylmethylamino group are essential for the antimalarial action of the compounds. The hydrophobic steroid part is likely to mediate membrane permeability.

Further information: PDF

TransMIT Gesellschaft für Technologietransfer mbH
Phone: +49 (0)641/943 64-12

Contact
Dr. Peter Stumpf

As Germany's association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At www.technologieallianz.de a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.

Comments (0)

Write a comment