New animal model for sporadic Alzheimer's Disease (AD)
Alzheimer's Disease (AD) is the main neurodegenerative disease worldwide. It places a large social and financial burden on society due to the need of life-long intensive care. There are two forms of AD identified by researchers, sporadic AD (SAD) and familial autosomal dominant AD (genetic background). Sporadic AD is the more common form, accounting for 90-95% of cases. Surprisingly, there is no animal model for the sporadic AD form available on the market.
Scientists of the University of Göttingen have now developed a transgenic mouse model for sporadic Alzheimer's Disease (TBA83). This is the first mouse model without any mutations showing neurological deficits by transgenic over-expressing of a particular form of amyloid beta peptides. The neurological phenotype resembles that of mouse models with neurodegeneration. We sell and license this new sporadic Alzheimer's Disease mice modell. Please contact us directly
Further Information: PDF
MBM ScienceBridge GmbH
Phone: (0551) 30724-151
Contact
Dr. Jens-Peter Horst
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Innovative 3D printed scaffolds offer new hope for bone healing
Researchers at the Institute for Bioengineering of Catalonia have developed novel 3D printed PLA-CaP scaffolds that promote blood vessel formation, ensuring better healing and regeneration of bone tissue. Bone is…
The surprising role of gut infection in Alzheimer’s disease
ASU- and Banner Alzheimer’s Institute-led study implicates link between a common virus and the disease, which travels from the gut to the brain and may be a target for antiviral…
Molecular gardening: New enzymes discovered for protein modification pruning
How deubiquitinases USP53 and USP54 cleave long polyubiquitin chains and how the former is linked to liver disease in children. Deubiquitinases (DUBs) are enzymes used by cells to trim protein…