Novel Modulators of TRAIL Signalling Pathway
The TNF-Related Apoptosis-Inducing Ligand (TRAIL) has been shown to be involved in apoptosis, cell survival, migration and proliferation. DKFZ inventors identified a multitude of genes encoding proteins that are associated with cell death induction by TRAIL. According to its individual function, inhibition or activation of the respective gene or gene product is assumed to have beneficial effects on cancer treatment. The technology can be used to screen for small molecules, antibodies or siRNAs that are capable of modulating TRAIL-induced cell death, thus having the potential to kill cancer cells or to sensitize cancer cells to established cancer drugs.
Further information: PDF
DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
Phone: +49-6221-42 2955
Contact
Dr. Ruth Herzog
As Germany's association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At www.technologieallianz.de a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Compact LCOS Microdisplay with Fast CMOS Backplane
…for High-Speed Light Modulation. Researchers from the Fraunhofer Institute for Photonic Microsystems IPMS, in collaboration with HOLOEYE Photonics AG, have developed a compact LCOS microdisplay with high refresh rates that…
New perspectives for material detection
CRC MARIE enters third funding period: A major success for terahertz research: Scientists at the University of Duisburg-Essen and the Ruhr University Bochum have been researching mobile material detection since…
CD Laboratory at TU Graz Researches New Semiconductor Materials
Using energy- and resource-saving methods, a research team at the Institute of Inorganic Chemistry at TU Graz aims to produce high-quality doped silicon layers for the electronics and solar industries….