Building blocks for new medications: the University of Graz is seeking a technology partner

Werner Seebacher, University of Graz Photo: University of Graz/Tzivanopoulos

The opiod fentanyl, which is used in anaesthesia and in the treatment of acute and chronic pain, is one of the most important drugs made with piperidin-4-ones. However, these intermediates are also essential for the manufacture of numerous other drugs with a wide range of medical applications.

“The synthesis technology we have developed gives us access to variants of piperidin-4-ones that cannot be obtained using traditional reaction pathways”, explains Werner Seebacher.

“What is special about our piperidin-4-ones is that they can be further modified as required. This opens up a range of new therapeutic possibilities”, says Seebacher, emphasising the significance of this technology, for which a European patent is now pending.

Further research is needed to discover exactly what those possibilities are. The University of Graz is currently looking for an industrial partner to produce these promising molecular components on a large scale and to press ahead with their development into new substances.

For further details see
https://static.uni-graz.at/fileadmin/forschen/dokumente/technologietransfer/Tech…

Priv.-Doz. Dr. Werner Seebacher
Institute of Pharmaceutical Sciences, University of Graz
Tel.: +43 (0)316 380-5383; 8648
E-mail: w.seebacher@uni-graz.at

Media Contact

Mag. Gudrun Pichler idw - Informationsdienst Wissenschaft

More Information:

https://www.uni-graz.at

All latest news from the category: Health and Medicine

This subject area encompasses research and studies in the field of human medicine.

Among the wide-ranging list of topics covered here are anesthesiology, anatomy, surgery, human genetics, hygiene and environmental medicine, internal medicine, neurology, pharmacology, physiology, urology and dental medicine.

Back to home

Comments (0)

Write a comment

Newest articles

NASA: Mystery of life’s handedness deepens

The mystery of why life uses molecules with specific orientations has deepened with a NASA-funded discovery that RNA — a key molecule thought to have potentially held the instructions for…

What are the effects of historic lithium mining on water quality?

Study reveals low levels of common contaminants but high levels of other elements in waters associated with an abandoned lithium mine. Lithium ore and mining waste from a historic lithium…

Quantum-inspired design boosts efficiency of heat-to-electricity conversion

Rice engineers take unconventional route to improving thermophotovoltaic systems. Researchers at Rice University have found a new way to improve a key element of thermophotovoltaic (TPV) systems, which convert heat…