Researchers led by CHLA’s Jonathan D. Santoro, MD, have identified signs of neuroinflammation and dysfunction of the blood-brain barrier among patients with Down syndrome Regression Disorder (DSRD). A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children’s Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in individuals with Down syndrome Regression Disorder (DSRD). The new study, “Evidence of blood–brain barrier dysfunction and CSF…
Online threats, hatred and harassment have led people who feel discriminated against to create digital spaces where they can feel safe. According to a new thesis from the University of Gothenburg, these spaces are characterised by clear rules and constant maintenance and monitoring. Much of social life today takes place online. Unfortunately, the worst aspects of interpersonal relationships also appear in the digital world. A study of 51 countries revealed that 38% of women had personally experienced online harassment. Bullying…
Virginia Tech scientists at the Fralin Biomedical Research Institute at VTC found practicing episodic future thinking both reduced impulsivity and enhanced connectivity in key regions of the brain Learning to think more about specific events in the future appears to reduce impulsivity, improve decision-making, and shows potential as a therapy for alcohol use disorder, a new Virginia Tech study found. The study, which involved 24 participants whose brains were scanned during both resting-state and task-based fMRI, showed brain connections were altered…
Researchers at the University of Gothenburg have discovered that what was previously thought to be a unique seaweed species of bladderwrack for the Baltic Sea is in fact a giant clone of common bladderwrack, perhaps the world’s largest clone overall. The discovery has implications for predicting the future of seaweed in a changing ocean. In the brakish waters of the Baltic Sea, bladderwrack is the dominant seaweed species as it is one of the few seaweed species that can tolerate…
Researchers at the University of Jena develop data sets for the description and recording of odours People all over the world largely agree on what the colour blue looks like or what the shape of a ball feels like. But when it comes to describing odours, opinions often differ. This is because, unlike the processing of wavelengths of light in the brain, which makes it possible to determine colours relatively clearly, it is still not easy to deduce the smell…
Cardiovascular diseases remain a leading cause of death worldwide, with platelet hyperactivity and subsequent thrombosis playing a pivotal role in these conditions. While intermittent fasting has long been recognized for its metabolic benefits, including improvements in metabolic diseases, weight loss, and even lifespan extension, its effect on platelet activation and thrombosis formation remains less understood. A recent study by Professor Junbo Ge team at Fudan University unveiled a novel mechanism by which intermittent fasting can significantly reduce the risk of…
Using an approach called DNA origami, scientists at Caltech have developed a technique that could lead to cheaper, reusable biomarker sensors for quickly detecting proteins in bodily fluids, eliminating the need to send samples out to lab centers for testing. “Our work provides a proof-of-concept showing a path to a single-step method that could be used to identify and measure nucleic acids and proteins,” says Paul Rothemund (BS ’94), a visiting associate at Caltech in computing and mathematical sciences, and…
They include polycystic ovary syndrome, endometriosis, heavy or irregular periods Having one or more common gynaecological disorders, such as endometriosis or heavy or irregular periods, may be linked to a heightened risk of heart disease and conditions that affect blood flow to the brain (cerebrovascular disease), finds a pooled data analysis of the available evidence published online in the journal Heart. Although the quality of the studies included in the analysis was variable, the researchers nevertheless conclude that clinicians and the…
Do you see the glass as half empty or half full? If you rewind to the start of the COVID-19 pandemic, chances are you experienced some level of pessimism. And who could blame you? With social isolation, health concerns and economic uncertainty, fear and anxiety became a daily reality for many. A team of researchers from Syracuse University and Michigan State University recently explored the personal characteristics that help people handle prolonged stressors, such as the pandemic. Led by Jeewon Oh,…
University’s $59 million research spending in 2024 boosted local, state and national economies while supporting student development University of Texas at Arlington research projects contributed $59 million to the national economy in 2024—an increase of 39% from 2023, according to a new report from the Institute for Research on Innovation and Science (IRIS). UTA has invested heavily in research infrastructure, purchasing cutting-edge scientific equipment and technology, such as North Texas’ most advanced gene sequencer and a super-sensitive magnetic resonance imaging machine for the Clinical…
With New Year resolutions in full swing and health tracking apps at our fingertips, new research reveals concerning links between health and fitness apps and disordered eating, body image concerns and excessive exercise. “Diet and fitness apps are marketed as tools to improve health, however they may also have unintended negative consequences, such as creating pressure to meet goals, concerns about body image as well as provoking feelings of guilt if goals aren’t achieved,” says Ms Isabella Anderberg in the…
A groundbreaking study led by a team of researchers at the University of Kentucky has revealed a surprising biochemical connection between plant immune responses and human neurological health. A groundbreaking study led by a team of researchers at the University of Kentucky’s Martin-Gatton College of Agriculture, Food and Environment has revealed a surprising biochemical connection between plant immune responses and human neurological health. Researchers have discovered that the metabolic pathways regulating vitamin B6 homeostasis — critical in certain forms of…
Ōtākou Whakaihu Waka research shows Aotearoa has been increasingly accepting new bird species from around the world since the start of the Ice Age, offering clues into future migration patterns. Since the Ice Age drastically changed the Aotearoa landscape from widely forested to grass and shrubland, researchers set out to determine which of our living and recently extinct birds are a result of existing lineages that adapted to their environment tens of millions of years ago and which are the…
EPFL scientists have developed a geometric deep learning method that can create a coherent picture of neuronal population activity during cognitive and motor tasks across experimental subjects and conditions In the parable of the blind men and the elephant, several blind men each describe a different part of an elephant they are touching – a sharp tusk, a flexible trunk, or a broad leg – and disagree about the animal’s true nature. The story illustrates the problem of understanding an…
The findings, demonstrated in mouse models and isolated human brain tissue, could expand treatment options for neurological and psychiatric diseases Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier. The findings, in mouse models and isolated human brain tissue, were published in the February 17 online…
Conservation researchers working on grassland restoration in Kenya found that larger areas of restored habitat reduced both social conflicts and human-wildlife conflicts Across Kenya, grasslands underpin people’s lives — as well as those of animals like elephants, giraffes, and hyenas. But the climate crisis is drying out these habitats, forcing people and animals to compete for resources, and increasing both community tensions and conflict between humans and wildlife. Researchers monitoring both grassland restoration and conflicts have now found that restoration…
Researchers at Brown University and Cincinnati Children’s found that suppressing opsin 3 in the brain of mice makes them eat less, raising new questions about the mechanisms involved in regulating human metabolism. Scientists discovered years ago that the hypothalamus — which helps to manage body temperature, hunger, sex drive, sleep and more — includes neurons that express the protein opsin 3 (OPN3). Far less clear, however, was what this light-sensing protein does so deep inside the brain. A study published in PNAS…