Health and Medicine

HIV patients at risk of a potentially fatal hypersensitive reaction to the antiretroviral drug abacavir could be identified by genetic testing before drug therapy has started, suggest authors of a fast-track study in this week’s issue of THE LANCET.

The use of the HIV antiretroviral drug abacavir, a potent HIV-1 nucleoside-analogue reverse-transcriptase inhibitor, is complicated by a potentially life-threatening hypersensitivity syndrome in about 5% of cases. Genetic factors influencing the

Authors of a French study in this week’s issue of THE LANCET highlight the link between a specific strain of the bacterium Staphylococcus aureus and a severe form of pneumonia in children.

Between 1986 and 1998, eight cases of community-acquired pneumonia due to S aureus strains carrying the gene for the Panton-Valentine leukocidin (PVL) were recorded in France, six of which were fatal. Jerome Etienne from the Centre Hospitalo-Universitaire of Lyon, France, aimed to assess the clinical feat

Alcoholics, especially those who relapse after frequent attempts to “dry out”, are damaging areas of their brain that recognise emotions, a University of Sussex study suggests.

Research on people’s responses to photographs of different emotional facial expressions shows that heavy drinkers who had previously tried to kick the bottle are more likely than either non-alcoholics, or alcoholics who had not previously experienced withdrawal symptoms, to read fear and sadness in all emotional expre

A team of researchers at the Universitat Autònoma de Barcelona, co-ordinated by Professors Josep Egozcue and Cristina Templado, has shown for the first time that the older a man is, the more probable it is that his spermatozoa will present chromosome anomalies. This is the first time that a lineal relationship has been established with precision between these two factors. The conclusions of this study, published in the European Journal of Human Genetics, increase the importance of the father’s age in

Women are seven times more likely than men to admit to a partner that they have a sexually acquired infection, reveals research in Sexually Transmitted Infections. The findings were irrespective of age or type of infection.

The findings are based on three population surveys of sexual behaviour carried out in France in the early to mid 1990s. Two of the surveys comprised a total of around 7000 adults; the third dealt with just over 6000 adolescents from 15 upwards. All those surveyed were ask

The issue of insulin-dependent diabetes has long been discussed. No wonder, as the problem concerns more than 5% of the world population. However, despite the enormous efforts and funds spent on its solution, the scientists so far have failed to replace the injections with pills. The difficulty is that insulin (like any other polypeptide) gets easily destroyed under the influence of proteolytic enzymes in the stomach and small intestines. The scientists have tried a variety of means: insulin plasters