Health and Medicine

Drug leads in protein that sends gut bacteria packing

A protein enables harmful Salmonella bacteria to switch from clinging to our gut lining to swimming off. This get-up-and-go is so crucial to Salmonella’s survival that the protein could prove to be a good target for drugs.

The Salmonella variant Typhimurium causes around 1.4 million cases of food poisoning in the United States each year, and about 1,000 deaths – mainly among infants and the elderly. The bug grips the gut

Genes are of little importance in the development of rheumatoid arthritis, finds a study in this week’s BMJ.

Researchers in Denmark surveyed over 37,000 twins about rheumatic diseases. Twin studies are one of the simplest ways to unravel the relative importance of genetic and environmental effects of a disease. Twins who reported that they had rheumatoid arthritis were invited to have a clinical examination.

Rheumatoid arthritis was verified in 13 identical and 36 non-identic

Over a third of women attending general practices have experienced physical violence, but doctors and nurses rarely ask about it. Researchers in this week’s BMJ ask:
Should women be screened for domestic violence when they visit their general practitioner?
Is there a high risk group of women for whom screening might be more appropriate?
Is screening acceptable to women?

A sample of women visiting 13 general practices in Hackney, east London were surveyed about different aspects o

Researchers at the University of Warwick`s Emergency Medicine Research Group have shown that the introduction of a separate stream for minor injuries in a hospital casualty department can reduce the overall number of trauma patients having to wait over an hour for treatment by around 30%.

Dr Matthew Cooke from the University of Warwick`s Centre for Primary Health Care Studies Emergency Medicine Research Group led a research team which looked at a scheme where the University Hospitals Coventr

Brain researchers in Amsterdam have observed a double control system in the hippocampus. This double control system contributes to the memory and ensures that the brain does not `crash`, as is the case during an epileptic seizure.

The neurobiologists from the University of Amsterdam carried out their observations on the hippocampus of rats. The hippocampus probably plays an important role in converting the short-term memory to the long-term memory.

The hippocampus contains two sorts

Many of today’s medicines were discovered by trial and error: a substance is found which helps alleviate the symptoms of a disease, and it may take years before scientists really understand how it works. Typically they find that a drug has its effects by attaching itself to a particular molecule in a cell and blocking part of its activity, the way you might prevent someone from turning a light on or off by putting a lock over the switch. Scientists now hope to take the opposite approach, and custom-d