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An amazingly sensitive method for selective analysis of amino acids, sugars, fatty acids, and other vital compounds has been developed by Russian scientists. This method allows determining even their trace quantities (fractions of nanograms). It is applicable in identifying cancerous cells and diagnostics of cancer at the earliest stage, when traditional diagnostics fail to catch sight of the disease.
Dr. Igor Revel’sky and his colleagues from the Moscow State University have dev
Moscow scientists have come forward with a new methodology of fighting fire, as fire can be stopped if deprived of airflow. It is possible that soon fire-wardens will extinguish fire not with water or foam, but with liquid nitrogen.
A bright-red fire-engine has been demonstrated at the exhibition ‘High tech-2004’, held at Krasnaya Presnya exhibition complex in Moscow. The engine was so huge, that inside its body it could accommodate a tank the size of a well-fed elephant. The
Purdue University chemists have developed a fast, efficient means of analyzing chemical samples found on surfaces, resulting in a device that could impact everything from airport security to astrobiology to forensic science.
A team, including R. Graham Cooks, has improved the mass spectrometer, a device well known to chemists for its ability to provide information on the composition of unknown substances. Mass spectrometers, essential tools in any modern chemistry lab, are often
Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics
A molecular mechanism that was formerly thought to be important only in bacteria has now been shown to be a potential target for an anticancer therapy based on antibiotic use. David Scheinberg and colleagues, at the Sloan-Kettering Institute, have been investigating an enzyme in humans that is similar to one in bacteria called peptide deformylase (Pdf) and have found that an antibioti
Requirement for sphingosine 1–phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference
Tumor growth and metastasis require new blood ves-sel growth, a process called angiogenesis. There are many factors involved in the nor-mal growth and stabilization of new blood vessels. One of these, sphingosine 1-phosphate receptor 1 (S1P1), is required during embryonic development to stabilize new blood vessels. Timothy Hla and colleagues, from the University of Con
Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis
As cancer progresses, cancer cells acquire the ability to become resistant to programmed-cell-death, called apoptosis. Understanding the molecular mechanisms involved in the regulation of apoptosis is key for developing proper cancer therapies. Survivin is a member of a family of proteins that are inhibitors of apoptosis (IAPs), but the means by which survivin inhibits apoptosis remains largely unknown. Dario