Life Sciences and Chemistry

Affymetrix Announces Commercial Launch of Single Array for Human Genome Expression Analysis

— More than 1 million probes analyze expression level of nearly 50,000 RNA transcripts and variants on a single array the size of a dime —

Affymetrix, Inc., (NASDAQ: AFFX) today launched its new GeneChip® brand Human Genome U133 Plus 2.0 Array, offering researchers the transcribed human genome on a single commercially available catalog microarray. The HG-U133 Plus 2.0 Array analyzes

An exciting and powerful service, using a new tool to investigate the genetics of human diseases, is announced today [1st October]. MRC geneservice, located in Cambridge, UK, is now able to supply researchers with fast and sensitive Affymetrix SNP genotyping in order to identify genome-wide linkage of diseases to particular markers in the human genome.

The GeneChipâ Mapping Assay kit from Affymetrix enables genotyping of more than 11,500 single nucleotide polymorphisms (SNPs) on a single arr

Researchers at the Howard Hughes Medical Institute in Boston have developed a fast and systematic method that could make it easier to understand how cells from complex animals work. Their results, published this week in Journal of Biology, should inspire scientists to perform comprehensive screens of the fruit fly genome to find molecules that control a variety of cellular processes. The research team, led by Norbert Perrimon, systematically inhibited the function of around 1,000 Drosophila

The contents of ancient pottery could help archaeologists resolve some longstanding disputes in the world of antiquities, thanks to scientists at Britain’s University of Bristol. The researchers have developed the first direct method for dating pottery by examining animal fats preserved inside the ceramic walls.

Archaeologists have long dated sites by the visual appearance of pottery fragments found around the site. The new analytical technique will allow archaeologists to more accurate

A non-human, cellular molecule is absorbed into human tissues as a result of eating red meat and milk products, according to a study by researchers at the University of California, San Diego (UCSD) School of Medicine, published online the week of September 29, 2003 in Proceedings of the National Academy of Sciences. The researchers also showed that the same foreign molecule generates an immune response that could potentially lead to inflammation in human tissues.

Several previous studies ha

A naturally occurring variation in an essential gene can suppress genetic mutations caused by retroviruses in mice, according to a new discovery by researchers at the University of California, San Diego (UCSD) School of Medicine.

Published in the September 28 online edition of Nature Genetics, and in the journal’s October issue, the study identified a novel change in mice in a gene called mRNA nuclear export factor 1 (Nxf1). This gene normally acts as part of the cell’s machinery for ensurin