Life Sciences and Chemistry

University of Utah biologist finds HIV gene makes a human gene turn bad

A human gene named ATR normally protects people by preventing the replication of cells damaged by radiation or toxic chemicals. Now, Utah and New York researchers have discovered how a gene in the AIDS virus hijacks the human gene and turns it into a weapon that prevents reproduction of immune-system white blood cells, leaving AIDS patients vulnerable to deadly infections and cancer.

The new study “puts

Two important questions face biologists studying the infectious proteins called prions: What stops prions that infect one species from infecting another species and what causes the invisible transmission barrier between species to fail sometimes?

In experiments with yeast prions reported in this week’s issue of Nature, Howard Hughes Medical Institute researchers have shown how point mutations in prions — which do not compromise their infectivity — can nevertheless cause prions to alter

Are there ’social behavior’ genes?

A rare genetic disorder may lead scientists to genes for social behavior, a Salk Institute study has found.

The study zeros in on the genes that may lead to the marked extroverted behavior seen in children with Williams syndrome, demonstrating that “hyper-sociability” – especially the drive to greet and interact with strangers — follows a unique developmental path.

The path is not only different from typical children bu

New discoveries about tiny genetic components called microRNAs explain why plant leaves are flat.

The study may be a first step, researchers say, in revolutionizing our understanding of how plants control their morphology, or shape. A plant’s ability to grow structures with a specific shape is critical to its normal function of capturing energy from the sun and producing products like grain and fiber.

As such, these findings could ultimately have profound implications fo

How vastly different animals arrive at the same body plan or pattern of ornamentation has long been a conundrum of developmental biology.

But now, thanks to the colorful derriere of a wild fruit fly, captured on a compost heap by a University of Wisconsin-Madison post-doctoral student, scientists have been able to document a rare example of molecular convergence, the process by which different animals use the same genes to repeatedly invent similar body patterns and structures.

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The advantages of production in plants

According to Navarre Public University lecturer, Angel Mingo, this novel system of protein production is highly advantageous, not only due to its reduced costs with respect to cell cultures in bioreactors, but also because the method is free of the health risks associated with animal cell culture.

Moreover, the technology involved is easily accessible and enables targeting the accumulation of protein to specific compartments and organs