Life Sciences and Chemistry

While picking apart the genetic makeup of the plant Arabidopsis, two Dartmouth researchers made a startling discovery. They found that approximately 36 percent of its genome is potentially regulated by the circadian clock, which is three and a half times more than had previously been estimated.

The study, which appears in the June issue of Plant Physiology, was conducted by C. Robertson McClung, Dartmouth professor of biological sciences, and Todd Michael, a former Dartmouth graduate studen

Researchers at the University of Pittsburgh have completed the first survey of the entire human genome for genes that affect the susceptibility of individuals to developing clinical depression.

George S. Zubenko, M.D., Ph.D., professor of psychiatry at the University of Pittsburgh School of Medicine and adjunct professor of biological sciences at Carnegie Mellon University and his team have located a number of chromosomal regions they say hold the genetic keys to a variety of mental illness

USC researchers have moved one step closer to understanding how the body fights harmful antigens – foreign molecules that trigger an immune response.

The team successfully simulated a mutation process that diversifies the proteins, or antibodies, responsible for immunity – a phenomenon known as somatic hypermutation. This process enables the body to fight off a wide range of diseases.

Their findings are detailed in the July 3 issue of the journal Nature.

“When performin

Madrid, Spain: Scientists believe that they are an important step nearer to success in creating an artificial egg from the combination of the nucleus of a somatic cell and an oocyte which has had its DNA-carrying nucleus removed, a conference of international fertility experts heard today (Tuesday 1 July).

Dr Peter Nagy, from Reproductive Biology Associates, Atlanta, collaborating with the University of Connecticut, USA, told the European Society of Human Reproduction and Embryology annual

About 200 genes identified

Tracing all the genetic changes that flow from a single mutation, UCSF scientists have identified the kinds of genes and systems in the body that ultimately allow a doubling of lifespan in the roundworm, C. elegans. Humans share many of these genes, and the researchers think the new findings offer clues to increasing human youthfulness and longevity as well.

Using DNA microarray technology, the researchers found that the single life-extending mutat

Research by Austrian geneticists has raised the possibility that stem cells[1] could be isolated from amniotic fluid – the protective ’bath water’ that surrounds the unborn baby.

Geneticist Professor Markus Hengstschläger and his team at the University of Vienna have isolated a subgroup of cells from amniotic fluid that express a protein called Oct-4 – known to be a key marker for human pluripotent stem cells.

Reporting the findings today (Monday 30 June) in Europe’