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U. of Colorado scientists discover four new kingdoms of life

University of Colorado at Boulder researchers have discovered four new kingdoms of life in the high alpine environment of Colorado, findings that have potential applications in the fields of agriculture and global change.

Doctoral student Allen Meyer and Professor Steven Schmidt of the environmental, population and organismic biology department discovered the new microbe kingdoms in barren, boulder-filled tundra slopes west of Boulder.

At altitudes of 11,000 feet to 13,000 feet in

Scientists Image Soft Tissues With New X-Ray Technique

Provides more information than conventional x-rays or other scanning methods

Scientists at the U.S. Department of Energy’s Brookhaven National Laboratory, in collaboration with researchers at Rush Medical College, have demonstrated the effectiveness of a novel x-ray imaging technology to visualize soft tissues of the human foot that are not visible with conventional x-rays. The technique, called Diffraction Enhanced Imaging (DEI), provides all of the information imparted by conventio

Getting through the matrix

MGH research suggests strategies for improving drug delivery to cancer cells

The best cancer drugs in the world are not much good if they cannot get to tumor cells. That problem has been challenging cancer physicians and researchers for years because the physical structure of many tumors can prevent anticancer agents from reaching their targets. In a study appearing in the June issue of Nature Medicine, researchers from Massachusetts General Hospital (MGH) describe a new technique for

Student-invented device eases installation of child car safety seats

Low-tech ‘Main Squeeze’ compresses for snug fit inside vehicle

Three Johns Hopkins University undergraduates have invented a low-tech tool that makes it much easier to properly install child safety seats in automobiles, ensuring a snug fit and maximum protection for the child.

The device, dubbed “Main Squeeze,” is intended to simplify the difficult task of compressing a child safety seat against a car’s permanent seat during installation. Incorrectly installed, a loose

Mutated protein combination tied to excessive sugar production

Study identifies potential target for diabetes drugs

Researchers at Dana-Farber Cancer Institute have traced runaway sugar production in the liver – an important feature of diabetes – to flaws in a two-protein combination at the heart of a molecular switch that responds to insulin.

The findings, to be posted by the journal Nature on its Web site on May 18, suggest that drugs designed to block the interaction of the two switch proteins might be effective in treating diabetes,

Chemists create unusual lariat RNA, a key intermediate in biological splicing

The production of lariat RNAs is a key step in the biologically important process of splicing. Because splicing changes the protein that is made from a given gene, a fundamental understanding of splicing is critical for comprehending the connections between genes and proteins. The study of splicing, however, has been very difficult in part because lariat RNAs have been nearly impossible to make artificially.

Now, chemistry professor Scott K. Silverman and graduate student Yangming Wang at th

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