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Because they are able to recognize a particular cell marker — a protein — antibodies are generally used to identify abnormal cells in the body. As such, they play a key role in diagnosis, treatment and basic research.
At the Institut Curie, CNRS research scientists have recently prepared a new type of antibody which for the first time combines several crucial features: it can be produced in a few days, it can be expressed directly in cells, and it is, moreover, sensitive to the shape of pro
In the race to stay one step ahead of drug-resistant bacteria, scientists from Lawrence Berkeley National Laboratory and the University of California at Berkeley obtained high-resolution images of a protein complex found in bacteria that repels a wide range of antibiotics.
The images, which appear in the May 9 issue of Science, offer new insight into how bacteria survive attacks from different antibiotics, a growing health problem called multidrug resistance. As the team learned, these robu
Farmers can prioritize areas within fields to reduce nitrate contamination
Fine-tuning fertilizer and irrigation management requires farmers to carefully balance optimizing yield and protecting groundwater quality. Some states even require farmers to use crop production practices to minimize nitrate leaching to groundwater in environmentally sensitive areas.
One such practice is using a nitrification inhibitor when applying nitrogen fertilizer, which helps protect nitrogen f
Prions—their existence is intriguing and their links to disease are unsettling. These unconventional infectious agents are involved in mad cow disease and other fatal brain illnesses in humans and animals, rattling prior assumptions about the spread of infections.
Dartmouth Medical School biochemists studying the mysteries of these prion particles have discovered a novel step in their formation. Their results, reported in a recent issue of Biochemistry could help provide a new approach for
Weizmann Institute study suggests that rising carbon dioxide levels might cause forests to spread into dry environments
Missing: around 7 billion tons of carbon dioxide (CO2), the main greenhouse gas charged with global warming. Every year, industry releases about 22 billion tons of carbon dioxide into the atmosphere. And every year, when scientists measure the rise of carbon dioxide in the atmosphere, it doesn’t add up – about half goes missing. Figuring in the amount that could be s
In a Perspective in the May 9 issue of Science, geochemist Don DePaolo and geodynamicist Michael Manga defend a fundamental assumption of Earth science, the mantle plume model of hotspots, against an outbreak of seismic skepticism.
DePaolo and Manga are members of Lawrence Berkeley National Laboratory’s Earth Sciences Division and the University of California at Berkeley’s Department of Earth and Planetary Science. DePaolo studies the chemical signatures of geological structures l