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New Molecular Self-Assembly Technique May Mimic how Cells Assemble Themselves

Researchers from the University of Pennsylvania and the University of Sheffield report in the Feb. 21 issue of Science that they have created tree-like molecules that assemble themselves into precisely structured building blocks of a quarter- million atoms. Such building blocks may be precursors to designing nanostructures for molecular electronics or photonics materials, which “steer” light in the same way computer chips steer electrons.

Virgil Percec, the P. Roy Vagelos Chair and Profes

Alcohol Researchers Identify a Genetic Basis of Pain Response

A common genetic variant influences individual responses and adaptation to pain and other stressful stimuli and may underlie vulnerability to many psychiatric and other complex diseases, reports David Goldman, M.D., Chief, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, and colleagues at NIAAA and the University of Michigan. COMT val158met Genotype Affects m-Opioid Neurotransmitter Responses to a Pain Stressor appears in the February 21 issue of Science (299:1240, 200

Fly mutation suggests link to human brain disease

Greater insight into human brain disease may emerge from studies of a new genetic mutation that causes adult fruit flies to develop symptoms akin to Alzheimer’s disease.

“This is the first fruit fly mutant to show some of the outward, physical manifestations common to certain major human neurodegenerative diseases,” said principal investigator Michael McKeown, a biology professor at Brown University.

A research team found the mutation in a gene they named “blue cheese.” Reporting i

Berkeley Scientists Create First 3-D Map of Protein Universe

The universe has been mapped! Not the universe of stars, planets, and black holes, but the protein universe, the vast assemblage of biological molecules that are the building blocks of living cells and control the chemical processes which make those cells work. Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley have created the first three-dimensional global map of the protein structure universe. This map provides important insight i

Bt Toxins Found to Kill Parasitic Roundworms

Biologists at the University of California, San Diego have discovered that Bacillus thuringiensis, or Bt — a bacterium that produces natural protein insecticides that have been used by organic farmers for five decades — can also produce similar natural proteins that kill nematodes.

The discovery could pave the way for the development of an inexpensive and environmentally safe means of controlling the parasitic roundworms that each year destroy billions of dollars in crops, cause debilitating

Mediterranean diet significantly lessens symptoms of rheumatoid arthritis

A Mediterranean diet significantly lessens the symptoms of rheumatoid arthritis, shows a small Swedish study in the Annals of the Rheumatic Diseases. But it takes a minimum of six weeks for the diet to take effect, the study shows.

The researchers were only able to study 51 people out of a possible 300, because of the various combinations of drugs patients were taking. In the end, 26 people with stable rheumatoid arthritis were assigned to an experimental Mediterranean/Cretan, diet for three

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