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In a demonstration of vaccine therapy’s potential for treating lung cancer, Dana-Farber Cancer Institute scientists and their associates report that a prototype vaccine boosted the natural immune response to tumors in a small group of patients with advanced non-small cell lung cancer (NSCLC). Moreover, the vaccine was found to be non-toxic and well-tolerated.
Published in the Feb. 15 issue of the Journal of Clinical Oncology, findings from the Phase I clinical trial will provide an impetus
When it comes to visual entertainment, three-dimensional viewing can be quite eye-opening. So, too, in science where a recent finding involving University of Iowa researchers used three-dimensional imaging to understand how a bacterial enzyme can take oxygen from air and use it to convert certain molecules into useful chemicals.
Specifically, the scientists saw that naphthalene dioxygenase, a bacterial enzyme, can bind oxygen (to iron) in a side-on fashion and add it on to naphthalene, a hy
Trees are better off if they produce large nuts. This is revealed in research by Patrick Jansen from Wageningen University. Scatterhoarding rodents appear to prefer burying larger nuts for later. The bigger the nut, the further it is buried from the tree and the more frequently it is forgotten.
Biologist Patrick Jansen investigated what happened to nuts as soon as they fell on the ground of the rainforest in French Guyana. He placed thousands of nuts on the ground in the forest. Each nut wa
Howard Hughes Medical Institute researchers are beginning to unravel how a mysterious sixth sense guides animal attraction. The scientists have made the first-ever recordings of patterns of brain activity in a mouse as it explores the sex and identity of a newly encountered animal.
The research team, led by Lawrence C. Katz, a Howard Hughes Medical Institute investigator at Duke University Medical Center, recorded the firing of neurons in the accessory olfactory bulb, part of a poorly under
The results from a longitudinal study of the relative frequency of various types of HIV mutations associated with the use of antiretroviral therapy (ART) were presented today at a meeting of leading AIDS researchers. The study showed that the prevalence of most key mutations associated with antiretroviral resistance have changed significantly from 1999-2002.
Specifically, the results showed that the prevalence of thymidine analog mutations (TAMs) and other key mutations associated with HIV
If you sniff a rose this Valentine’s Day, your brain will recognize almost a hundred different molecules that collectively give the flower its heady scent-but how? Scientists are now discovering how the brain identifies odors and their mysterious counterparts, the pheromones. New research, to be presented today at the American Association for the Advancement of Science (AAAS) Annual Meeting and forthcoming in the journal, Science, explains how the mouse brain is exquisitely tuned to recognize an