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Fighting fire with fire? Vaccine based on chimp virus shows promise against HIV

In a new study in mice, a modified form of an innocuous chimpanzee virus has shown marked potency as a protective vaccine against HIV, itself believed to have crossed into the human population from chimpanzees sometime in the 1930s. The study, led by researchers at The Wistar Institute, appears in the February issue of the Journal of Immunology.

“Our results show this new vaccine is capable of inducing the kind of powerful immune response that we and others believe will be critical for cont

Oxygen key switch in transforming adult stem cells from fat into cartilage

In their ongoing research on turning adult stem cells isolated from fat into cartilage, Duke University Medical Center researchers have demonstrated that the level of oxygen present during the transformation process is a key switch in stimulating the stem cells to change.

Their findings were presented today (Feb. 2, 2003) at the annual meeting of the Orthopedic Research Society.

Using a biochemical cocktail of steroids and growth factors, the researchers have “retrained” specific

Using sewage sludge as fertilizer

Using organic waste presents a win-win situation for municipalities, agriculture

Sewage sludge has the potential to boost production for certain crops while addressing the increase in the amount of waste and the growing scarcity of landfills, according to scientists at the University of Florida.

Using organic waste as fertilizer is not a new concept. Before the 1940s, when synthetic nitrogen fertilizer became widely available, animal manure and human waste were commonly used

Using RNA interference to tune gene activity in stem cells

New method for the study and treatment of disease

The application of RNA interference (RNAi) to the study of mammalian biology and disease has the potential to revolutionize biomedical research and speed the development of novel therapeutic strategies.

A series of studies by Greg Hannon at Cold Spring Harbor Laboratory (CSHL) have revealed a great deal of information about the mechanism of RNAi, as well as how RNAi can be adapted for use in medical research. These and other

News for every parent: Ways to protect your infant from sudden death

New research examines why African-American infants are at greater risk

Why is Sudden Infant Death Syndrome more common among African-American infants than in babies of other races?

Research in this month’s issue of Pediatrics suggests the answer might lie in the high prevalence of African-American infants who have died suddenly after being put to sleep in adult beds or on surfaces other than cribs, such as sofas. It urges public health officials to make African American

Young plant’s natural defenses amount to more than just its seed

Chua lab discovers protein that regulates early growth arrest

For an infant plant, the world outside of its seed is not always a friendly place. Drought, wind, ice and other harsh conditions would threaten its well-being were it not for the shelter of its seed. Consequently, the decision to shed this weatherproof coat in order to begin to grow is perhaps the most critical a plant will ever make: once it stretches its fragile stem up toward the sky, there’s no turning back to the

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