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Human heart tissue generated from embryonic stem cells

Human heart tissue has for the first time been created in the laboratory.

Generated from embryonic stem cells at the Technion-Israel Institute of Technology, the tissue could be used for testing and creating new drugs, for genetic studies, for tissue engineering and for studying the effects of various stresses on the heart.

“Everyone imagines the possibilities of embryonic stem cells in repairing broken hearts, but stem cell technology offers even more — and it offers it muc

Rotation oscillation toothbrushes proven more effective than ’sonic’ technology

Nearly four decades of research conclude that power toothbrushes with rotation oscillation action, such as the Oral-B 3D Excel, are demonstrably more effective in removing plaque and reducing gingivitis than other types of power toothbrushes — including those featuring “sonic” technology — according to an international study announced today at the Forsyth Institute conference on evidence-based dentistry.

Half of adults age 18 or older have some evidence of gingivitis, the earliest

Designer molecules correct RNA splicing defects: New strategy for treating many diseases

With a high-tech fix for faulty cellular editing, scientists at Cold Spring Harbor Laboratory have moved a step closer to developing treatments for a host of diseases as diverse as breast cancer, muscular dystrophy, and cystic fibrosis.

Many human diseases have been linked to defects in a cellular editing process called pre-messenger RNA splicing. Adrian Krainer, a molecular biologist at Cold Spring Harbor Laboratory, has spent years investigating this complex editing process, which t

Blocking one protein helps cancer cells die of natural causes

Researchers have identified a protein fragment that keeps at least one major tumor suppressor gene from preventing cancer like it should. The fragment belongs to a class of proteins known as apoptotic enhancers (ASPP), named for their ability to stimulate programmed cell death, or apoptosis, by the p53 gene.

But a study published in Nature Genetics finds that one member of this group, called iASPP, actually inhibits p53’s normal cell killing power. When iASPP levels were reduced in experime

First Swedish study on health promotion

In recent years a new view of health has emerged. The change has been so momentous that it has been called a paradigm shift. But what kind of social transformation are we experiencing? What is actually meant by ‘health promotion’? This is what Peter Korp at the University of Trollhättan/Uddevalla has investigated in his doctoral dissertation in sociology. The study is the first to be carried out on the basis of conditions in Sweden.

The view of how health is dealt with in society ha

Radiation-resistant organism reveals its defense strategies

The secret to its strength is a ring, Weizmann Institute researchers report in Science

Weizmann Institute scientists have found what makes the bacterium Deinococcus radiodurans the most radiation-resistant organism in the world: The microbe’s DNA is packed tightly into a ring. The findings, published in the January 10 issue of Science, solve a mystery that has long engaged the scientific community.

The red bacterium can withstand 1.5 million rads – a thousand times more tha

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