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New study pursues the impact of pregnancy on drug efficacy

Whether pregnant women with conditions ranging from ulcers to AIDS should keep taking the same doses of medicine they took before pregnancy is a question Medical College of Georgia researchers want answered.

They are betting they’ll find that to maintain efficacy, pregnant women will need higher doses and that the placenta, a 2-pound temporary organ of pregnancy, is why.

“The idea that we are developing is that pregnant women are so different from non-pregnant women in ter

UWE Builds Device to Ease Discomfort for Prosthesis Wearers

For wearers of prosthetic or false limbs, the comfort and effectiveness of the socket fit is crucial. New ways of measuring and solving socket pressure points – using load analysis techniques from the aircraft industry – have been developed by engineering and computing researchers at the University of the West of England.

A team from UWE’’s Faculty of Computing, Engineering and Mathematical Sciences has just been awarded a grant of £52,000 by the charity Remedi to further their res

Conservation of the natural land resources of the Mekong delta

Physical fertility of typical Mekong delta soils (Vietnam) and land suitability assessment for alternative crops with rice cultivation

Most of the soils in the Mekong delta, Vietnam are formed and developed during the Holocene period. The first Viet people came to reclaim and exploit this plain at the beginning of the 17th century. As a result, in the middle of the 19th century, the Mekong delta had become the largest region of agricultural production, essentially rice produce for ma

FaME38: Helping engineers studying critical materials

Airplane wings or railway rails are examples of mechanical components constantly submitted to stress. They consist of materials (metal alloys) with properties that may change under stress. To understand and improve such materials, it is essential to observe them on a microscopic scale. The ESRF and the ILL make today a step forward into looking deep inside engineering components. Thanks to the use of complementary neutron and synchrotron X-ray beams, these two centres offer a unique tool to measure s

Metre-Long Medusas And Molluscs Seize The Ocean

The first outbreak of the evolution of multicellular organisms falls on the Wend, the last period of the Proterozoic (Precambrian), about 620-550 million years ago. At that time, climate of our planet was rather cold, and glaciers that covered the single supercontinent nearly reached the equator. The cold is beneficial for the evolution of sea creatures.

In modern seas, significant concentrations of dissolved oxygen, phosphates, and the organic matter provide for a high biological productiv

Exosomes, novel antigen bearers in "antitumor vaccination", yield some of their secrets

Exosomes are minute, natural membrane vesicles secreted by various types of cells of the immune system. They are of enormous interest to oncologists, who are now using them in clinical trials as tumor-antigen bearers to trigger tumor rejection by the body.

On the basis of studies in vitro and in mice, INSERM doctors and research scientists at the Institut Curie proposed a novel mode of functioning of exosomes in the December 2002 issue of Nature Immunology. It seems that exosomes can indire

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