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University of Pittsburgh researchers develop a urinary catheter to monitor oxygen delivery to organs

Monitoring oxygen delivery to organs is vital for treatment of trauma and critical care patients

When treating trauma and critical care patients after severe hemorrhagic shock, hours and days count. That’s why University of Pittsburgh researchers, working with an Israeli physiology professor, saw the need to develop a “smart” urinary catheter – which is typically used for bladder drainage – that they modified in order to provide clinicians with immediate information about the amo

Cipro, related antibiotics over-prescribed, fueling microbe resistance

A new study heightens concerns that Cipro and related broad-spectrum antibiotics known as fluoroquinolones are being over-prescribed, accelerating bacterial resistance to the drugs and reducing their ability to treat infections.

The UCSF-led study evaluated the records of more than 13,000 patients across the country hospitalized for “community-acquired” pneumonia – pneumonia that developed before the patient was hospitalized. The researchers found that fluoroquinolones were widely prescribe

Findings aid understanding of neurodegenerative diseases

Northwestern University scientists have made a key molecular discovery that has implications for a wide range of diseases characterized by the loss of nerve function, including Huntington’s, Parkinson’s, Alzheimer’s and Lou Gehrig’s diseases, cystic fibrosis and Creutzfeldt-Jakob disease, the human form of mad cow disease.

The findings, which will be published in the Oct. 1 issue of Nature Cell Biology, could lead to an understanding of how to prevent these diseases and

Researchers develop calculator to better determine prognosis for patients with melanoma

Tool provides physicians with better understanding of survival rates to help patients make more informed treatment decisions

The following stories detail news from the current issue of Mayo Clinic Proceedings. They are intended for use as individual stories or as part of a larger story on a particular medical topic.

Mayo Clinic researchers have developed another user-friendly calculator to aid physicians in better understanding complex cancer data and helping their patients

New protease inhibitor held HIV at undetectable levels for four years

A study from The Feinberg School of Medicine has shown that the protease inhibitor lopinavir/ritonavir (Kaletra®) suppressed HIV to undetectable levels and was well tolerated through four years of treatment in patients who had not previously received antiretroviral therapy.

To date in the Kaletra® study, none of the patients has developed resistance to Kaletra® or other protease inhibitors. Kaletra® is thus far the only protease inhibitor for which resistance has not been observed in patient

TRUST 2002 study shows levofloxacin resistance remains rare in S. pneumoniae

Correlations of antimicrobial resistance among s. pneumoniae in the U.S.: 2001-2002 trust surveillance

Resistance to commonly prescribed antibiotics is increasing among Streptococcus pneumoniae, a leading cause of respiratory illness. In the early 1990s, resistance to penicillin became a concern, however, in the last five years (1998-2002), S. pneumoniae has also exhibited increased resistance to other antibiotic classes, such as the macrolides (e.g. azithromycin, clarithromycin) and

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