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UB Scientists Report Fast, Simple Method of Generating "Designer" RNA Catalysts for Proteomics

Artificial “Sugazyme” catalyzes synthesis of novel proteins with special features

University at Buffalo chemists have developed a remarkably simple and effective biotechnological method for synthesis of novel proteins using amino acids that do not occur in nature by using unique, programmable ribozymes (enzymes made of RNA, or ribonucleic acid) that they evolved in the lab.

The technology, described in the July issue of Nature Biotechnology, provides a potentially important

Study confirms air pollution linked to slowed lung function growth in children

Kids growing up in smoggy areas again have been found to suffer the effects of pollution, especially acid vapor, according to findings from the University of Southern California-led Children’s Health Study.

The 10-year-long Children’s Health Study is considered one of the nation’s most comprehensive studies to date of the long-term effects of smog on children. The new findings address the development of lung function in children, showing that lung function growth of kids in p

New treatment for skeletal metastases

Norwegian and Swedish researchers have developed a new type of internal radiation therapy for cancer that has spread to skeletal tissue. Experience from an early patient test is optimistic, according to a report being presented at the 18th International Cancer Congress in Oslo this week.

Many patients with advanced breast, prostate or lung cancer experience metastasis to skeletal tissue. This is often a source of pain and suffering.

Exterior irradiation and medication, including ra

See Spot work

Scientists discover Spot 42 function in the galactose operon

Although the E. coli galactose operon is a staple of most biology textbooks, a new report in the July 1 issue of Genes & Development shows that our understanding of this common example of bacterial gene regulation is still evolving.
Dr. Poul Valentin-Hansen and colleagues at the University of Southern Denmark report that a small RNA, called Spot 42, functions by an antisense mechanism to differentially regulate gene exp

Efficient plastic nuggets key to agricultural plastic waste disposal

A process that would be a plastics recycler’s nightmare may help farmers deal with the disposal of agricultural and domestic plastics by creating burnable, energy-efficient plastic nuggets, according to a Penn State agricultural engineer.

“In plastics recycling there are two unbreakable rules,” says James W. Garthe, instructor in agricultural engineering and cooperative extension specialist. “You cannot mix types of plastic, and the plastics must be clean. This process does both since

Latest ice core may solve mystery of ancient volcanic eruptions

A team of Ohio State University researchers has returned from an expedition in southeastern Alaska with the longest ice core ever drilled from a mountainous glacier.

The core measures 460 meters (1,509 feet) and is 150 meters (492 feet) longer than the previous longest core – a record of ice from the Guliya ice cap in western China that eventually relinquished a climate record stretching back 760,000 years – the oldest such record retrieved to date.

Until the new core is analyzed in

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