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Salmonella bacteria sequenced

Bugs behind typhoid and food poisoning give up genetic secrets.

Two teams have sequenced the genomes of two Salmonella bacteria. One is responsible for typhoid; the other causes food poisoning.

The genomes should lead to new ways to diagnose, treat and vaccinate against both diseases. Comparing the sequences should also clarify why the closely related bugs behave quite differently.

The two strains are called Typhi and Typhimurium. Typhi, the typhoid bug, infects onl

A rosy glow

Genetic engineering gives us the fluorescent daisy.

It’s produced in Italy and guaranteed to make the face of that special someone light up. It’s the luminous bouquet. Under ultraviolet light the apparently normal blooms glow an unearthly green.

“The fluorescent flowers show that genetic engineering can be developed just for beauty,” says their developer, Tito Schiva of the Experimental Institute of Floriculture, San Remo. The technique should work for any white flower, Sch

Anthrax action shapes up

Researchers find two new leads for anti-anthrax drugs.

As fears over bioterrorism attacks spiral, researchers are making progress towards better anthrax drugs – but these are unlikely to reach the drugstore soon.

Of ten confirmed anthrax cases in the United States by Monday, four have been of the severe, inhaled form against which antibiotics often fail. By the time drugs destroy the bacteria responsible, Bacillus anthracis, the organisms have released enough lethal toxin t

Meat fuelled Midas’ rot

The gold-loving king’s rich diet may have hastened his decay.

Legend says that lust for gold was the cause of King Midas’ downfall. But his appetite for meat may have destroyed the final monument to his greatness 1 .

A mound excavated 44 years ago in Turkey is thought to be the resting place of the eighth-century BC ruler of Phrygia. The large tomb, although built of durable cedar wood, is in surprisingly bad shape, says geophysicist Timothy Filley of the Car

Flies caught napping

Researchers discover two molecules that help fruitflies sleep.

Mutant flies that lack the chemicals sleep more. In mammals the same molecules are also involved in learning and memory, supporting the idea that one function of sleep is to consolidate our record of the day’s experiences 1 .

The molecules are cyclic AMP and CREB, chemical messengers that work within cells. Cyclic AMP activates CREB, which then switches on genes.

Joan Hendricks, of th

Breast cancer screens scrutinised

Study questions whether mammography saves lives.

Breast-cancer screening programmes may not save lives, according to a new examination of clinical trials. The controversial findings have led to calls for a re-evaluation of the routine monitoring procedure undergone by numerous women.

Mammography, X-ray breast imaging, is used in Europe and the United States to catch cancers early. “We’ve based a national screening programme on a set of results which do not stand up to scrut

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