Im Rahmen des Sonderforschungsbereichs werden die Analyse von Pilz- und Pflanzeninhaltsstoffen, ihre Biosynthese, die Regulation ihrer Biosynthese, die Signalfunktion solcher Metabolite und die Rolle von Sekundärmetaboliten im Stoffwechsel untersucht. Darüber hinaus wird die Entwicklung neuer und verbesserter NMR-Methoden und Rechenverfahren für die Strukturaufklärung vorangetrieben. Es wird erwartet, dass sich hieraus langfristig neue Ansätze für die Herstellung pharmazeutisch und landwirtschaftlich wirksa
Ziel ist es, die Regulation der Ressourcenverteilung zwischen und innerhalb von Nutzpflanzen aus Land- und Forstwirtschaft sowie die hierbei, unter dem Einfluss pflanzlicher Konkurrenten, Wirt-Parasit-Interaktion und Mykorrhizen sich einstellenden stofflich-energetischen ,,Kosten-Nutzen-Bilanzen“ zu klären. Das ,,Dilemma“ der Pflanze, Primär- und Sekundärstoffwechsel im Spannungsfeld zwischen Wachstumsprozessen und effizienter Konkurrenz gegenüber Nachbarindividuen einerseits und der Parasitenabwehr anderer
Es sollen biologische Erkennungsprozesse unter Verwendung molekularer Bibliotheken untersucht werden. Nahziel ist die Bearbeitung ausgesuchter Modellbeispiele aus Immunologie, Zellbiologie und Strukturbiologie. Unter Verwendung von Peptid-Bibliotheken wird beispielsweise die Corticotropin Releasing Hormon Rezeptor-Wechselwirkung, die Interaktion von a2–Makroglobulin mit verschiedenen Zytokinen sowie die Spezifität der MHC-Peptid-Erkennung untersucht. Röntgenkristallstrukturanalyse, NMR und andere physikalis
The Biosciences Federation, an umbrella organisation representing over 60,000 life scientists, will be launched today at the House of Lords.
The Federation has been formed by an amalgamation of the Institute of Biology and the UK Life Sciences Committee.
It has over 20 member societies, in disciplines as disparate as ecology and neuroscience.
The main aims of the Federation are to promote dialogue between life scientists and to provide a single coherent voice for bioscient
An analysis of pesticides that accumulate in Arctic waterways is giving scientists insight into the fate of such pollutants once they settle in polar regions.
The Arctic holds a telltale record of how humans have used chemicals globally during the past several decades. These cold corners of the earth act as a sink of sorts – chemicals used in industry and agriculture worldwide slowly migrate to and settle there – in sizeable quantities – in water, snow, ice, soil and vegetation.
In an attempt to find new regulators of the immune system, a team of researchers at Rigel Pharmaceuticals, Inc. have created a successful method for discovering molecules that are involved in signalling pathways. As published this week in the Journal of Biology, the team conducted a functional genome-wide screen and discovered novel modulators of T-cell receptor signalling that could aid in the development of drugs that target the immune response.
T cells are an integral part of the immune r
NASA’s Coronal Diagnostic Experiment (CODEX) is ready to launch to the International Space Station to reveal new details about the solar wind including its origin and its evolution. Launching in…
In space exploration, long-distance optical links can now be used to transmit images, films and data from space probes to Earth using light. But in order for the signals to…
… in thunderstorm cloud-top corona discharges. A team of researchers from the University of Science and Technology of China (USTC), led by Professors LEI Jiuhou, ZHU Baoyou, and Associate Professor…
By applying an electric field, the movement of microswimmers can be manipulated. Scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS), the Indian Institute of Technology (IIT) Hyderabad…
Researchers at The Jackson Laboratory have developed a new combination of imaging and computational methods to study connections between immune cells in breast cancer and melanoma. A growing cancer is…
Roughly one third of patients with depressive symptoms have elevated levels of inflammation. Inflammation is however often only measured using very broad and unspecific markers. To better understand the connection…
Small drops, big impact: Over time, rain can damage the surfaces of rotor blades. This reduces the efficiency and profitability of wind turbines, especially at sea. Researchers from institutions of…
…takes sensor technology to extreme conditions. Researchers at Tampere University have developed the world’s first soft touchpad that can sense the force, area and location of contact without electricity. The…
Polaritons are coupled excitations of electromagnetic waves with either charged particles or vibrations in the atomic lattice of a given material. They are widely used in nanophotonics because of their…
Researchers discover new magnetic and electronic properties in kagome magnet thin films. A discovery by Rice University physicists and collaborators is unlocking a new understanding of magnetism and electronic interactions…
– Wireless Aggregation of Health Data. Health data, distributed across various applications, could be unified in a digital medical twin: This is how doctors could improve patient care with the…
Large-scale optical programmable logic array can execute complex models like Conway’s Game of Life, marking a significant advancement in optical computing. Researchers have long sought to harness the power of…