The world´s first human test of a vaccine against the prevalent subtype of HIV in sub-Saharan African and Asia, where millions have the virus that causes AIDS, is now under way. The clinical trial uses novel technology pioneered by scientists at the University of North Carolina at Chapel Hill School of Medicine and the U. S. Army Medical Research Institute of Infectious Diseases.

The phase I trial began July 17 at Johns Hopkins University. An adult male, at low risk for HIV infection, was th

Reprogammable microarrays

Physicists at the Georgia Institute of Technology have demonstrated a new optical technique for controlling the flow of very small volumes of fluids over solid surfaces. The technique, which relies on changes in surface tension prompted by optically-generated thermal gradients, could provide the foundation for a new generation of dynamically reprogrammable microfluidic devices.

A paper describing the technique is the cover story for the August 1 iss

Classification of quantum phenomena critical to high-temp superconductivity

A team of physicists led by researchers at Rice University has developed the first thermodynamic method for systematically classifying quantum phase transitions, mysterious electromagnetic transformations that are widely believed to play a critical role in high-temperature superconductivity.

The new research is described in two papers – one theoretical and one experimental – in the Aug. 8 issue of Phy

It lacks the warm bedside manner of Marcus Welby or Dr. Kildare, but a high-tech robot being tested at The Johns Hopkins Hospital could be used to link patients with their physicians in a whole new way.

Vaguely resembling a human torso, in a Star Wars R2D2 sort of way, the robot sports a computer screen for a head, a video camera for eyes and a speaker for a mouth. It walks, in a manner of speaking, on three balls, talks, and most importantly, listens. “That´s because the robot is directly

It may be a right-handed world, but recent Purdue University research indicates that the first building blocks of life were lefties – and suggests why, on a molecular level, all living things remain southpaws to this day.

In findings that may shed light on the earliest days of evolutionary history, R. Graham Cooks and a team of Purdue chemists have reported experiments that suggest why all 20 of the amino acids that comprise living things exhibit “left-handed chirality,” which refe

Why are elephants bigger than mice? The main reason is that mice have fewer cells. Research published in Journal of Biology this week uncovers a key pathway that controls the number of cells in an animal, thereby controlling its size.

Ernst Hafen and his colleagues from the University of Zürich used fruit flies to investigate the role of the insulin-signalling pathway and in particular a molecule called FOXO. If insulin signalling is reduced, for example by starving developing fly lar