May explain life extension via calorie restriction
Researchers at Harvard Medical School (HMS) have discovered that a gene in yeast is a key regulator of lifespan. The gene, PNC1, is the first that has been shown to respond specifically to environmental factors known to affect lifespan in many organisms. A team led by David Sinclair, assistant professor of pathology at HMS, found that PNC1 is required for the lifespan extension that yeast experience under calorie restriction. A yeast
Duke University Medical Center biochemists have developed a computational method to design proteins that can specifically detect a wide array of chemicals from TNT to brain chemicals involved in neurological disorders. In a paper in the May 8, 2003, issue of the journal Nature, they demonstrate the breadth of their design method, and also that such sensor proteins can be re-incorporated into cells to activate cellular signaling and genetic pathways.
The researchers said their achievement c
Genetics may play a role in the success of anti-cancer therapy, according to researchers at the Research Institute of the McGill University Health Centre (MUHC) and the Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis – Jewish General Hospital. Their study, published in todays issue of Clinical Cancer Research, shows that some colorectal cancer patients with a particular gene mutation respond much better to therapy than those without this genetic change.
“Our fin
While it is well-established that roads can help spread invasive weeds, one new study shows that improved roads are worse than primitive ones, while another suggests that roadless areas act as refuges for native species against invasions.
Cheatgrass, knapweeds and other non-native plants have invaded nearly 125 million acres of the American West. Roads promote invasion because vehicles can transport non-native seeds into uninfested areas, and disturbed roadsides give weed seeds a place to g
Exactly how a person’s eyes respond to low levels of light is even more crucial than doctors have thought in deciding who is and who isn’t a good candidate to have laser vision correction surgery, according to results announced today at the annual meeting of the Association for Research in Vision and Ophthalmology in Ft. Lauderdale. The findings should help doctors choose patients who are likely to fare well with the surgery, and to forego recommending treatment for others.
In the earliest d
A research team led by The University of Texas M. D. Anderson Cancer Center has tested a novel “viral smart bomb” therapy that can completely eradicate brain tumors in mice, while leaving normal brain tissue alone.
The therapy, known as Delta-24-RGD, is thought to be the first treatment for malignant glioma, the deadliest form of brain cancer. It is a new-generation “replication-competent oncolytic” adenovirus therapy –– defined as a therapeutic virus that can spread, wavelike, throughout a
Although Mars is currently a cold, dry planet, geological evidence suggests that liquid water existed there around 3 to 4 billion years ago. Where there is water, there is usually…
A new paper unravels the mysteries of a bizarre physical state known as the pseudogap, which has close ties to the sought-after state called high-temperature superconductivity, in which electrical resistance…
Researchers from Delft University of Technology in The Netherlands have been able to initiate a controlled movement in the very heart of an atom. They caused the atomic nucleus to…
Nanoparticle potential found for assessing kidneys. In a study published July 29 in Advanced Materials, University of Texas at Dallas researchers found that X-rays of the kidneys using gold nanoparticles as…
Future treatment of high cholesterol gene defect. CRISPR-Cas systems, which consist of protein and RNA components, originally developed as a natural defense mechanism of bacteria to fend off intruding viruses….
Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology,…
… that can harvest energy at room temperature. Researchers have succeeded in developing a framework for organic thermoelectric power generation from ambient temperature and without a temperature gradient. Researchers have…
The global use of lithium-ion batteries has doubled in just the past four years, generating alarming amounts of battery waste containing many hazardous substances. The need for effective recycling methods…
A new study led by researchers at the University of Minnesota Twin Cities is providing new insights into how next-generation electronics, including memory components in computers, breakdown or degrade over…
… shape-shift into versatile robots. Scientists at MPI-IS have developed electrically driven robotic components, called HEXEL modules, which can snap together into high-speed reconfigurable robots. Magnets embedded along the outside…
The AQT quantum computer, featuring 20 qubits based on trapped-ion technology, is now operational at LRZ’s Quantum Integration Centre (QIC), making it the first of its kind in a computing…
The CHAI joint project aims to optimize corrosion management in ports and waterways. The federal state of Schleswig-Holstein is funding the CHAI research project with a total of 900,000 euros….