Finding is a significant step toward new insights for designing combination chemotherapy

Investigators at St. Jude Children’s Research Hospital have discovered numerous genes that alter their level of activity in characteristic patterns in response to specific chemotherapy treatments. The genes were identified in the leukemia cells of children undergoing chemotherapy for acute lymphoblastic leukemia (ALL).

The researchers say this finding is a significant step in the emergin

New digital tools

To survive and thrive in this century, business leaders need to hardwire new technologies into their playbooks to create enduring enterprises.

Many factors, from the need to export beyond national borders to the inexorable shift to intellectual capital, are driving change, but none is more important than the rise of the Internet and digital technologies. Like the steam engine or the assembly line, the Net and digital technologies have already become an adva

Scientists report for the first time that “baby” teeth, the temporary teeth that children begin losing around their sixth birthday, contain a rich supply of stem cells in their dental pulp. The researchers say this unexpected discovery could have important implications because the stem cells remain alive inside the tooth for a short time after it falls out of a child’s mouth, suggesting the cells could be readily harvested for research.

According to the scientists, who published their

Rutgers Associate Professor Suzie Chen has discovered a gene responsible for melanoma, the most aggressive form of malignant skin cancer. A paper describing the research by Chen and her colleagues at the National Human Genome Research Institute will be published online by Nature Genetics on April 21, and will appear subsequently in a print issue of the journal.

Melanoma may appear in places that never see sun, spread to other parts of the body and become lethal. This type of cancer is not g

VLT Spectra Indicate Shortest-Known-Period Planet Orbiting OGLE-TR-3

More than 100 exoplanets in orbit around stars other than the Sun have been found so far. But while their orbital periods and distances from their central stars are well known, their true masses cannot be determined with certainty, only lower limits.

This fundamental limitation is inherent in the common observational method to discover exoplanets – the measurements of small and regular changes in the centra

The relationship between leguminous plants such as peas and beans and nitrogen-fixing bacteria is even closer than previously thought, with bacteria acting like an intrinsic part of the plant, according to research published in the journal Nature today.

Researchers from the University of Reading and the John Innes Centre, Norwich, have found that nitrogen-fixing bacteria provide more than just a supply of useable nitrogen to the plants. They have found that amino acid cycling between the pl