An enzyme found only in the liver and intestines may play a crucial role in the development of hardening of the arteries — or atherosclerosis, a research team from Wake Forest University Baptist Medical Center and the University of California, San Francisco, report in the Proceedings of the National Academy of Sciences.

The narrowing of arteries through atherosclerosis is a major contributor to heart attacks and strokes.

The confirmation of the relationship between the enzyme, AC

Next-Generation IT Platform for Topological Proteomics to be Created

MelTec GmbH and the Fraunhofer Institute for Applied Information Technology FIT today signed a collaboration agreement to develop an information technology platform for the management and interpretation of high-throughput experiments analysing protein networks of whole cells in situ, also known as topological proteomics or toponomics. MelTec continuously generates large data sets to decipher the toponome of cells an

atugen AG, a private company focused on the elucidation of disease pathways, today announced the identification of a novel cancer target that appears to play an important role in tumor growth and metastasis. atugen’s research group has demonstrated that inhibition of the novel target, Atu027, which has homology to protein kinases, results in blockage of tumor growth of human prostate carcinoma cells in orthotopic mouse models. atugen has demonstrated that human prostate tumor cells engineered to expr

The discovery of 160 year old records in the archives of the Royal Society, London, has given scientists further evidence that Australian sea levels are rising.

Observations taken at Tasmania’s Port Arthur convict settlement 160 years ago by an amateur meteorologist have been compared with data from a modern tide gauge.

“There is a rate of sea level rise of about 1mm a year, consistent with other Australian observations,” says Dr David Pugh, from the UK’s Southampton Ocean

Groundbreaking study in female mice links estrogen, lower blood pressure, and insulin resistance, despite a high fructose diet

Bethesda, MD – High-fructose corn syrup replaced sucrose (table sugar) as a sweetener in most grocery products some 20 years ago. Today, about nine percent of the average dietary energy intake in the U.S. comes from fructose. However, a number of nutritionists are alarmed by the amount of the public’s consumption, as previous research has demonstrated that a

By using mouse models, the EU-funded DEPROHEALTH-project has demonstrated that some lactobacilli can have a beneficial effect on intestinal inflammation and infections. The major target disease in these mouse studies has been inflammation of the bowel. For this purpose, engineered lactobacilli were constructed. The modified strains that are most promising produce fair levels of an effective compound (an interleukine) that helps preventing the inflammation caused by bacteria. Four of the most promi