Biochemist Daniel R. Gallie at the University of California, Riverside and his research team of Zhong Chen, Todd Young, Jun Ling, and Su-Chih Chang report in the March 18, 2003, issue of the Proceedings of the National Academy of Sciences (PNAS) that they have developed technology that increases the amount of vitamin C in plants, including grains, by increasing the amount of the enzyme that is responsible for recycling vitamin C. “The ability to increase the level of vitamin C in plant food will enh

The JNK signaling pathway allows cells to respond to changes in their extracellular environment and in doing so, controls many aspects of cell function including cell proliferation, differentiation and death. Studies have also shown that this pathway plays a role in cancer, although it has been unclear whether active JNK signaling can accelerate or protect cells from becoming cancerous. Several studies using cultured cells have suggested that JNK signaling may be important for promoting tumor cell de

Breakthrough could help resolve serious problems in oceanography and climate research

Scientists at Johns Hopkins University and the University of California-Irvine have finally been able to field-test theories about how wind transfers energy to ocean waves, a topic of debate since the 19th century that had previously proved impossible to settle experimentally.

The new results may help lead the way to the resolution of a longstanding problem in scientists’ understanding

Patients who have had colorectal cancer may reduce their risk of suffering a recurrence by taking an aspirin daily, according to a new study conducted by a University of North Carolina at Chapel Hill physician and colleagues around the United States.

The study showed that subjects who took 325 milligrams of aspirin each day had a 35 percent lower risk of developing polyps in their colons during the period examined than did patients who received an inactive placebo. Polyps are considered pre

New work by researchers in the Kimmel Cancer Center at Johns Hopkins may allow them to halt the smoking-induced cellular events that lead to 99 percent of all small cell lung cancers (SCLC). The research is reported in the March 5, 2003, issue of Nature.

The researchers found that a primitive cellular pathway, called Sonic Hedgehog (named for the cartoon character and spiky hairs it develops on fruit flies) stays turned on long after it should be turned off in some lung cancers.

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Long-time farmers’ friend shows promise against parasitic worms

Roundworms, hookworms, watch out. Scientists this week announced that a soil bacterium’s crystal proteins, long an effective weapon against many insect pests, are toxic to some nematodes, too.

The crystal proteins – created by some strains of Bacillus thuringiensis, more commonly known as Bt – thwart the development of some nematodes and kill others outright. The findings raise the possibility that thes