For more than a decade, researchers have been trying to create accurate computer models of Escherichia coli (E. coli), a bacterium that makes headlines for its varied roles in food poisoning, drug manufacture and biological research.

By combining laboratory data with recently completed genetic databases, researchers can craft digital colonies of organisms that mimic, and even predict, some behaviors of living cells to an accuracy of about 75 percent.

Now, NSF-supported researchers

Scientists open door to possible new treatments for urinary tract infections

Clingy bacteria often spell trouble. Scientists at Washington University School of Medicine in St. Louis have discovered how bacteria manufacture hair-like fibers used to cling to the lining of the kidney and bladder where they cause urinary tract infections (UTIs). The results are published in the Nov. 15 issue of the journal Cell.

“Our findings should lead to new drugs to treat UTIs by blocking t

A gene may be responsible for halting the spread of cancer through the body, according to scientists at the University of Virginia Health System. The gene, called RhoGDI2, could also be used as a warning to help catch the spread of cancer in patients earlier. A multidisciplinary team of scientists, led by Dr. Dan Theodorescu, professor of urology and molecular physiology at U.Va., used advanced DNA technology to discover that low levels of RhoGDI2 were found more often in invasive cancer than in loca

A team of scientists from the U.S. Department of Energy’s Brookhaven National Laboratory, Harvard University, and Bar-Ilan University in Israel have grown ultrathin films made of organic molecules on the surface of liquid mercury. The results, reported in the November 15, 2002, issue of Science, reveal a series of new molecular structures that could lead to novel applications in nanotechnology, which involves manipulating materials at the atomic scale.

Growing molecular films on liquid

Scientists at The Scripps Research Institute report

Professor Richard A. Lerner, M.D., Associate Professor Paul Wentworth, Jr., Ph.D., and a team of investigators at The Scripps Research Institute (TSRI) is reporting that antibodies can destroy bacteria, playing a hitherto unknown role in immune protection. Furthermore, the team found that when antibodies do this, they appear to produce the reactive gas ozone.

“[Ozone] has never been considered a part of biology before,” say

It is already possible for PC users to switch off simply by winking their eyes, but it is expected this will soon be possible wirelessly! Now in its start-up phase, the Academy of Finland’s Research Programme on Proactive Information Technology or PROACT includes a project dedicated to the development of wireless technology. One of the applications is a PC interface controlled by eye movement.

All five Academy research programmes launched during 2002 will benefit from international funding.