The results from a longitudinal study of the relative frequency of various types of HIV mutations associated with the use of antiretroviral therapy (ART) were presented today at a meeting of leading AIDS researchers. The study showed that the prevalence of most key mutations associated with antiretroviral resistance have changed significantly from 1999-2002.

Specifically, the results showed that the prevalence of thymidine analog mutations (TAMs) and other key mutations associated with HIV

Smithsonian scientist challenges results of recent study

Late last year, Frédéric Achard and colleagues published a controversial article in which they contended that earlier estimates of worldwide tropical deforestation and atmospheric carbon emissions were too high. In the February 14 issue of Science, Philip Fearnside from the National Institute for Amazonian Research in Brazil, and William Laurance from the Smithsonian Tropical Research Institute in Panama argue that the Achard st

In a demonstration of vaccine therapy’s potential for treating lung cancer, Dana-Farber Cancer Institute scientists and their associates report that a prototype vaccine boosted the natural immune response to tumors in a small group of patients with advanced non-small cell lung cancer (NSCLC). Moreover, the vaccine was found to be non-toxic and well-tolerated.

Published in the Feb. 15 issue of the Journal of Clinical Oncology, findings from the Phase I clinical trial will provide an impetus

Howard Hughes Medical Institute researchers are beginning to unravel how a mysterious sixth sense guides animal attraction. The scientists have made the first-ever recordings of patterns of brain activity in a mouse as it explores the sex and identity of a newly encountered animal.

The research team, led by Lawrence C. Katz, a Howard Hughes Medical Institute investigator at Duke University Medical Center, recorded the firing of neurons in the accessory olfactory bulb, part of a poorly under

When it comes to visual entertainment, three-dimensional viewing can be quite eye-opening. So, too, in science where a recent finding involving University of Iowa researchers used three-dimensional imaging to understand how a bacterial enzyme can take oxygen from air and use it to convert certain molecules into useful chemicals.

Specifically, the scientists saw that naphthalene dioxygenase, a bacterial enzyme, can bind oxygen (to iron) in a side-on fashion and add it on to naphthalene, a hy

Scientists at the Department of Global Ecology of the Carnegie Institution of Washington in Stanford, California, have found that climate trends significantly affect corn and soybean yields. David Lobell and Dr. Gregory Asner analyzed 17 years of data on crop yields, temperature, precipitation, and solar radiation throughout the U.S. for their study and published their results in the February 14, 2003, issue of Science.

The investigation showed that gradual increases in temperature cause si