Staphylococcus aureus is an opportunistic pathogen with a diverse battery of virulence factors, each of which can act alone or in concert in the development of persistent and sometimes lethal infections such as sepsis, toxic shock syndrome, food poisoning and severe skin diseases.

Staphylococcal infections begin when the organism gains access to host tissues or the adjoining blood supply through breaches in the skin. More than 20% of healthy humans are natural carriers of S. aureus, 10%-20%

Most cancer patients are not killed by their primary tumors but succumb to metastatic disease. The most common human cancers–lung, breast, and prostate–frequently spread to bone, causing suffering and morbidity through pain, fractures, and nerve compression syndromes.

Tumor cells enter bones through blood and lymphatic vessels. In order to establish bone metastases, they have to influence bone metabolism. Most breast cancers that spread to bone express high levels of parathyroid hormone r

The future of nanoelectronics looks promising. Built with nanotubes and various self-assembling molecular structures, this technology may revolutionize the electronic world by replacing the silicon transistor in approximately ten years.

Chemically synthesized nano building blocks are expected to replace semiconductor logic and memory devices and target niche applications over the next decade.

“In 20 to 50 years, we will likely see wide-ranging use of self-assembly,” says Technical I

UCSF-led scientists have identified the first “master” molecule in the cell nucleus that controls the action of hundreds of different genes at once through its action on enzymes. The broad-acting molecule affects enzymes that restructure chromosomes, exposing genes to proteins that can then trigger key gene processes, including the start of protein production and copying and repairing of genes.

The molecule’s broad effect on a number of genes may allow organisms – including humans — to

Researchers in the Materials Sciences Division (MSD) of Lawrence Berkeley National Laboratory, working with crystal-growing teams at Cornell University and Japan’s Ritsumeikan University, have learned that the band gap of the semiconductor indium nitride is not 2 electron volts (2 eV) as previously thought, but instead is a much lower 0.7 eV.

The serendipitous discovery means that a single system of alloys incorporating indium, gallium, and nitrogen can convert virtually the full spectru

When they make their first public demonstration of tele-immersion at this week’s Super Computing 2002 conference in Baltimore, computer scientists will also attain another first: a “network computer” that processes data at a location far removed from either input or output.

While the tele-immersion system will gather and display information in side-by-side booths at the Baltimore Convention Center, actual data processing will occur some 250 miles away at the Pittsburgh Supercomputing C