Key step in process of developing targeted therapeutics to combat epilepsy

Scientists from Toronto’s Princess Margaret Hospital are able to depict for the first time how an important molecule called IP3 and its receptor interact to control calcium levels in cells, a process that is vital to normal brain function.

The study is published in this week’s edition of the international scientific journal Nature, and is a collaboration between scientists at Princess Margar

A new clinical trial has shown that reducing the interval between successive doses of a commonly used chemotherapy regimen improves survival in women whose breast cancer has spread to the lymph nodes. While previous research has evaluated the use of various forms of “dose dense” chemotherapy, this is the first major controlled study to show a clear survival benefit for women with node-positive breast cancer. The study was conducted by Cancer and Leukemia Group B (CALGB) for the Breast Cancer Intergro

Through precise control of the etching process, an inventor in Oxford University’s Photofabrication Unit has made the reliable production of High Resolution Printed Circuit Boards (PCBs) with conductors down to 10 µm wide more of a cost-effective reality.

With increasing demands for greater miniaturisation and the use of flexible circuitry, the need for improved fabrication methods for high resolution printed circuit boards is becoming more important. PCBs currently include conductors with

Biodiversity worldwide may be decreasing, but at smaller scales it is increasing or at least changing in composition, suggesting the need for a dramatic shift in the current focus of ecological research. These changes may undermine the functioning of local ecosystems, according to an article in December’s American Naturalist.
The authors –– Dov F. Sax, assistant research scientist at the University of California, Santa Barbara; Steven D. Gaines, director of the Marine Science Institute and a

Sure Santa Claus asks boys and girls what toys they want, but, why they want them is a better question. The answer may have to do with a biological pre-wiring that influences boys’ and girls’ preferences based on the early roles of males and females, says a Texas A&M University psychologist.

It’s commonly believed that boys and girls learn what types of toys they should like based solely on society’s expectations, but psychologist Gerianne Alexander’s work with verv

Developed at MGH, digital tomosynthesis may better identify malignant lesions

A new approach to mammography, developed by researchers at Massachusetts General Hospital (MGH), holds the potential for greatly improving the detection of breast lesions and the ability to predict whether they are benign or malignant. In a presentation earlier this month at the scientific assembly of the Radiological Society of North America (RSNA), Elizabeth Rafferty, MD, of the MGH Breast Imaging Service