Morphochem AG, a leader in novel chemistries for small molecule drug discovery, has announced that one of its leading programmes, inhibitors of blood coagulation Factor Xa, led to the identification of novel, orally available anti-thrombotics in preclinical studies. Details of these preclinical studies will be presented at a meeting of investment analysts and pharmaceutical executives to be held in Basel on 21st November.
Commenting on the Factor Xa programme, Dr Lutz Weber, CEO of Morphochem sa
Aspirin conclusively reduces the risk of a first heart attack by 32%, according to a new report by researchers at Mount Sinai Medical Center & Miami Heart Institute. The findings were presented today at the American Heart Associations Scientific Sessions in Chicago.
Charles H. Hennekens, MD, co-director of Cardiovascular Research, published the first randomized trial of aspirin in primary prevention. Under his direction, Rachel S. Eidelman, MD, a cardiology fellow, performed a detaile
Childhood Strokes Have Complex Causes
Patient Evaluations Should Seek Treatable Risk Factors
When children suffer strokes, physicians should look beyond the obvious causes to find risk factors that could be treated, say the authors of large British study of childhood stroke published November 15 in the on-line edition of the Annals of Neurology, the scientific journal of the American Neurological Association.
About half the children in the study of more than 200 stroke v
Scientists at UCL have recreated earthquakes in the laboratory for the first time allowing them to better understand the origin of the largest and most violent earthquakes.
This is the first time scientists have been able to generate and observe deep and intermediate focus earthquakes in the laboratory, recreating the exact pressure and temperature conditions of the deep earth. Their results have helped elucidate the origin of some of the largest and most violent earthquakes to occur on ear
A research team of the Public University of Navarre (Basque Country), under the supervision of professors Jesus Zurita Gabasa and Jesus Mª Pintor Borobia, from the department of Mechanical, Energetic and Materials Engineering, is working in a project to improve and optimise vibrating tables that are used in the agri-foodstuffs sector. The project is being done by the request of the company Tecnologia Alimentaria Urtasun from Navarre (Basque Country) , manufacturer of this kind of machinery.
In October, the Upper Atmosphere Research Satellite (UARS) completed the first measurement of the solar ultraviolet radiation spectrum over the duration of an 11 year solar cycle, a period marked by cyclical shifts in the Suns activity. This long measurement record by two instruments aboard UARS will give researchers better insight into how fluctuations in the Suns energy affect ozone and the Earths climate. In turn, the dataset gives scientists tools to document the influence of ma
– new calculation confirms standard model of particle physics. Contribution of hadronic vacuum polarization determined with unprecedented accuracy. The magnetic moment of the muon is an important precision parameter for…
Technique may prevent formation of unwanted waves that siphon off needed energy. Heating plasma to the ultra-high temperatures needed for fusion reactions requires more than turning the dial on a…
An international team of astronomers, led by researchers from the Astronomical Observatory of the University of Warsaw, have identified a new class of cosmic X-ray sources. The findings have been…
How deubiquitinases USP53 and USP54 cleave long polyubiquitin chains and how the former is linked to liver disease in children. Deubiquitinases (DUBs) are enzymes used by cells to trim protein…
Conceptual blueprint to analyze experimental catalyst data. Machine learning (ML) models have recently become popular in the field of heterogeneous catalyst design. The inherent complexity of the interactions between catalyst…
Antibody that Neutralizes Inhibitory Factors Involved in Nerve Regeneration Leads to Enhanced Motor Function after Acute Spinal Cord Injury. Researchers at 13 clinics in Germany, Switzerland, the Czech Republic and…
How simulations help manufacturing of modern displays. Modern materials must be recyclable and sustainable. Consumer electronics is no exception, with organic light-emitting diodes (OLEDs) taking over modern televisions and portable…
“Neurons that fire together, wire together” describes the neural plasticity seen in human brains, but neurons grown in a dish don’t seem to follow these rules. Neurons that are cultured…
The quest for sustainable energy solutions has been a major focus of scientific research for decades. Solar energy, a clean and renewable source, has emerged as a promising alternative to…
With a processing speed a billion times faster than nature, chip-based laser neuron could help advance AI tasks such as pattern recognition and sequence prediction. Researchers have developed a laser-based…
New technology could remotely identify various types of plastics, offering a valuable tool for future monitoring and analysis of oceanic plastic pollution. Researchers have developed a new hyperspectral Raman imaging…
Artificial Intelligence (AI) has established a strong presence across industries, large and small. The “VoBaKI” research project has empowered small and medium-sized enterprises (SMEs) with an innovative tool to independently…