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New real-time Hsp90 high throughput screening method using fluorescence resonance energy transfer (FRET)

The molecular chaperone heat shock protein 90 (Hsp90) couples ATP hydrolysis

to conformational changes driving a reaction cycle that is required

Biofilm-inhibiting effect and anti-infective activity of Arylisochinolines

Supply of novel, highly effective and non-toxic agents

– Improved prevention of biofilm-formation

– Treatment of infectious diseasesFurther Information: PDF Bayerische Patentallianz GmbH…

Antitumoral and antiinfective compounds isolated from tropical lianas

Plants are an important source of pharmacologically active substances. The tropical

lianas of the families Dioncophyllaceae and Ancistrocladaceae are rich in…

Pathogen resistance to plants and increased biomass by carbohydrate alteration

Carbohydrates are generated by photosynthesis in green plant cells. In higher plants

they are transported from green tissues (source tissue) to other parts…

Archaeal Expression System (Sulfolobus shuttle vector)

Sulfolobus spp., a thermoacidophilic crenarchaeote, can be easily grown in

the laboratory and is interesting from a biotechnological point of view. Due

Nucleoside analogs in combination with Nodal, SHH or mTOR inhibitors for eliminating epithelial cancer stem cells (CSC)

Epithelial cancers are among the most

frequent causes of death. Especially

pancreatic carcinomas are characterized

by early metastatic spread and…

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