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Bioactive pre-tubulysins and use thereof

Pre-tubulysin was already claimed as a hypothetically common preliminary stage of tubulysins in 2004. Now it is available by synthesis and can be used for…

Gene regulation – it's all in the DNA

Scientists in Cambridge, UK, using a mouse with a human chromosome in its cells, discovered that gene expression, contrary to what was previously thought, is…

Tick-borne encephalitis virus reveals its access code

Flaviviruses such as tick-borne encephalitis virus (TBEV), yellow fever, and dengue are dangerous human pathogens. These membrane-encircled viruses enter cells…

molecular marker for minimally invasive diagnostics of either cerebral tumours or inflammable diseases

The work group of Prof. Dr. Eckart Meese at Saarland University identified special features of tumour cells that could constitute a basis for an improved…

New Enzyme Anhydrofructose-Reductase

The invention affects the novel bacterial enzyme 1,5-anhydro-D-fructose-reductase. In a regio- and stereoselective reaction 1,5-anhydro-D-fructose (AF) is…

Novel viral expression system

A novel yeast expression system was developed in the lab of Prof. Manfred Schmitt from the Department of Applied Molecular Biology of the Saarland University…

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