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There are already several methods for the introduction of modifications in proteins which make use of the particular nucleophilicity of the cysteine side…
The invention at hand provides novel, very hydrophobic ionic liquids as well as methods for the production thereof.<p>
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Self-assembling monolayers (SAMs) allow for the targeted modification of surface areas. Previously known methods for the production of SAMs are carried out…
The treatment of lung and respiratory diseases, such as asthma and Chronic Obstructive Pulmonary Disease (COPD), pneumonia and pulmonary hypertension, is…
All previously known synthesis procedures for the production of adamantane derivatives require drastic reaction conditions like, for example, the use of…
The effect of the intravenously administered fibrinogen IIb/IIIa receptor antagonist Tirofiban as a thrombocyte aggregation inhibitor is known and well investigated. Now, for the first time, the dispersal of Tirofiban in the form of an aerosol has been achieved, which allows application of the produced aerosol via inhalation. This has the advantage that the active ingredients are reabsorbed very quickly after deposition and rapidly reach a therapeutically active drug level in the blood, which leads to life-saving thrombocyte aggregation inhibition. With this the possibility for acute and immediate treatment of diseases which are caused by or in conjunction with thrombus formation is finally available.