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Discovery has implications for wide range of diseases

A team of international researchers has discovered that a specific gene on chromosome 15 regulates inflammation, a finding with implications for a wide range of disorders, including cancer, cardiovascular disease, diabetes, obesity, Alzheimer’s, and infections. The findings are published in the October 9 online issue of Nature Genetics.

Investigators believe this discovery will be of great interest to biomedical

Colliding compact stars likely cause of short but powerful gamma-ray bursts

An international team of scientists using three NASA satellites and a host of ground-based telescopes believes it has solved the greatest remaining mystery of the mysterious gamma-ray bursts (GRBs), the most powerful explosions in the universe. The shorter of two versions of these bursts appear to be caused by the collision of closely orbiting neutron stars or one of those compact stars and a black hole,

Johns Hopkins Kimmel Cancer Center researchers have linked alterations in a gene, called Rsf-1, to the most deadly ovarian cancers. The scientists say the discovery is the first to establish a role for the gene in ovarian cancer and may lead to a test that can predict, early on, which patients will develop aggressive disease.

“We hope new therapies can be tailored to target Rsf-1, in the same way that Herceptin for breast cancer attacks the Her2/neu gene pathway,” says Tian-Li

Researchers at Purdue University who developed the first system capable of searching a company’s catalog of three-dimensional parts created with computer-aided design software are now providing a method to evaluate how well such systems work.

Shape-search engines could save time and millions of dollars annually by making it easier for companies to “reuse” previous designs, reducing redundancy and streamlining a company’s supply chain. The systems will enable companies to b

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors, a discovery that could pave the way for more effective cancer treatments.

The Hopkins team, in conjunction with researchers at the J. Craig Venter Institute in Rockville, Md., discovered DNA abnormalities in two tyrosine kinase proteins already known to disrupt normal cell activity and contribute to tumor formation.

The discovery of these mutations is especially significant, t

ESA’s Mars Express mission has been extended by one Martian year, or about 23 months, from the beginning of December 2005.

The decision, taken on 19 October by ESA’s Science Programme Committee, allows the spacecraft orbiting the Red Planet to continue building on the legacy of its own scientific success. Co-ordinated from the beginning with the Mars science and exploration activities of other agencies, Mars Express has revealed an increasingly complex picture of Mars.