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A newly discovered genetic defect might represent an important risk factor for major depression, a condition which effects 20 million people in the U.S., according to Duke University Medical Center researchers. The mutation in the gene — whose protein product plays a primary role in synthesizing the brain chemical serotonin — could lead to the first diagnostic test for genetic predisposition to depression, the team said.
“Abnormalities in brain levels of serotonin have been wide
Service Will Allow Patients Direct Access to Latest Research
Scientific publishers and the nation’s leading voluntary health organizations have announced a groundbreaking initiative to help patients and caregivers close a critical information gap.
Scheduled to launch as a pilot project in Spring 2005, patientINFORM (www.patientinform.org) is a free, online service dedicated to disseminating original medical research directly to consumers. A collaborative effort of leadin
The connection between species richness and area occupied, recognized by biologists for more than a hundred years as a fundamental ecological relationship in plant and in animal communities, has been discerned for the first time at the microbial level.
A pair of papers in the Dec. 9 issue of the journal Nature, one focused on bacteria and another on a microbial fungi, shows that the number of species present – the diversity – increases as the area they occupy increases. “The resul
Using hairlike microelectrodes and computer analysis, neurobiologists at Duke University Medical Center have demonstrated that they can see the detailed instant-to-instant electrical “brainscape” of neural activity across a living brain.
In their study on rats, they demonstrated that they could distinguish in unprecedented detail the patterns of brain activity — including fleeting changes in communication among brain structures — in awake animals, as they fall sleep and as they
Scientists determine how ’trump card’ protein blocks DNA replication
New research at Rice University is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA replication, showing for the first time how a key protein “trumps” its rivals and shuts down cell division while DNA repairs take place.
The work, sponsored by the American Cancer Society, appears in the Dec. 8 issue of the journal Structure. It could aid drug makers in d
As members of an international research consortium, a group of GSF scientists led Randolph B Caldwell and Jean-Marie Buerstedde contributed to the annotation of the complete chicken genome. This first genome sequence of a bird is not only of great importance for research projects with chickens, but it will also lead to a better understanding of the previously decoded human genome.
Originally, the GSF research project aimed at identifying active genes in a particularly interestin