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A gene hunt being carried out at the University of Leicester for a skin disorder that affects over one million people in the UK alone has made a new breakthrough which could lead to the design of new and more targeted drugs.

The research team in the University of Leicester Division of Medical Genetics, led by Professor Richard Trembath, has been investigating Psoriasis – an inflammatory skin condition – for a number of years. Now Professor Trembath believes the research has made

Could boost surveillance in public places

A new three-dimensional multi-camera system that allows viewers to search areas from various vantage points could one day boost surveillance in public places such as airports and train stations, say University of Toronto researchers. The system – based on ideas published in the October proceedings of the 2004 IEEE International Conference on Systems, Man and Cybernetics – allows users to capture images of a scene from multiple angles and

Fibrin gel matrix-based vessel ready for test transplantation after only two weeks in culture

The search for a stable, renewable source of blood vessels, especially for potential use in heart bypass surgery, has reached a milestone at the State University of New York at Buffalo. A multi-disciplinary team at SUNY Buffalo designed tissue engineered blood vessels (TEVs) using a matrix of vascular smooth muscle embedded in fibrin gels. After only two weeks in culture, the TEVs show

Scientists from three countries study innovative DNA transport element

Treating genetic diseases by introducing functional genes into the human organism: researchers from three European countries are aiming for a breakthrough in this process, known as gene therapy, using a new methodology. The network of scientists, including the German Research Centre for Biotechnology in Braunschweig (GBF), is working to further develop a certain type of DNA element, called an episome, for this

Caspase levels are associated with liver injury

Caspase activity in the sera of patients with chronic hepatitis C infection (HCV) may be a more sensitive measure of liver injury than conventional surrogate markers like aminotransferases, according to a new study published in the November 2004 issue of Hepatology. Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD), published by John Wiley & Sons, Inc., is available online via Wiley

In August and September of this year, three powerful icebreakers transited to the North Pole in search of a climate record stored in sediments below the Arctic Ocean floor. During the spectacular Arctic Coring Expedition (ACEX), conducted by the Integrated Ocean Drilling Program (IODP), 340 meters of sediment core were retrieved from the bottom of the Arctic Ocean — a true “first.” With these sediments in hand, earth scientists for the first time can move away from pure speculation about the