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Solving the mystery of the dancer mice, and cleft lip too

By watching mice “dance” and comparing the DNA of the dancers to their flat-footed siblings, scientists have discovered a genetic cause of cleft lip and palate in mice, a finding that is already being used to search for a similar genetic defect in humans.

A team led by Rulang Jiang of the Center for Oral Biology at the University of Rochester Medical Center found that a gene known as Tbx10 is responsible for causing cleft lip and palate in mice. The group, which reported its results April 2

Cell Therapy for Parkinson’s Disease

According to research work at the University Hospital, cell therapy could improve many of the motor deficits of patients with Parkinson’s Disease.

With Parkinson’s a degeneration of cell groups takes place and so, from a conceptual perspective, the perfect treatment would be to replace the cells lost. The big drawback in the search for a suitable cell is to find one that survives for a lengthy period within the brain, that integrates well into the brain structures in order to comply w

NJIT grad student and professor take ride of their lives in vomit comet

Actually, doctoral candidate Alexandre Ermoline, North Arlington, NJ and NJIT Assistant Research Professor Mirko Schoenitz , PhD, Princeton, NJ, took four rides over four days aboard a KC-135 aircraft operated by the National Aeronautics and Space Administration (NASA). NASA operates the craft at the Lyndon B. Johnson Space Center in Houston which advances research in microgravity.

“Moving without gravity is an unusual sensation,” recently recalled Schoenitz. “I’ve heard people describ

Airport baggage screeners may need continuing education, study indicates

Baggage screeners have just seconds amid loud airport noises and the pressure of rushed airline travelers to scan X-rays of carry-on items for weapons. How good they are at finding one may depend on the specificity of their training, say researchers at the University of Illinois at Urbana-Champaign.

The findings, published in the May issue of the journal Psychological Science, suggest that initial training of federal airport screeners needs to last long enough for them to be exposed to a var

Genome-wide screen reveals new tricks of old genes

Process shows how mounds of data can be effectively managed

Johns Hopkins scientists have successfully used new techniques to search the yeast genome for genes that help keep copied chromosomes together, protecting the integrity of the organism’s genetic material during cell division.

By combining two genome-wide screens, the researchers were able to narrow down the dozens of genes identified by the first screen to just 17 that made both cut-offs — a number small enough

Hopkins scientists overcome main obstacle to making tons of short, drug-like proteins

Two Johns Hopkins scientists have figured out a simple way to make millions upon millions of drug-like peptides quickly and efficiently, overcoming a major hurdle to creating and screening huge “libraries” of these super-short proteins for use in drug development.

“Our work dramatically increases the complexity of peptide libraries that can be created and the speed with which they can be made and processed,” says Chuck Merryman, Ph.D., a postdoctoral fellow who developed the new technique. “

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