Insights gained from extensive studies in mice may someday lead to treatments for comparable neurodegenerative diseases in humans
Scientists at Jefferson Medical College and the University of Michigan have uncovered a gene defect responsible for a muscle-wasting, neurodegenerative disease in mice known as mnd2. Their results may provide insights into the molecular origins of other such diseases in humans, including Parkinson’s disease.
In an online report on October 8 in the
Researchers have demonstrated that Methotrexate, a promising drug to treat hearing loss in patients with autoimmune inner ear disease (AIED), proved no more effective than placebo in a recently concluded four-year study.
In findings published in the October 8, 2003 issue of the Journal of the American Medical Association (JAMA), a team headed by University of California, San Diego (UCSD) Professor and Chief of Otolaryngology Head and Neck Surgery, Jeffrey Harris, M.D., also noted that the s
Vanderbilt is one of nine US sites
Vanderbilt University Medical Center is participating in worldwide tests of a potential vaccine that can stimulate important immune responses against the virus that causes AIDS.
This is the first candidate vaccine against the human immunodeficiency virus (HIV) to be studied simultaneously in so many locations, from Brazil to Thailand, according to Merck & Co. Inc., which developed the vaccine.
Vanderbilt currently is testing six p
Discovery could lead to development of protein-targeting drugs, OHSU researchers say
When HIV enters the human body, a fierce battle ensues between a ruthless viral protein and our long-misunderstood innate protection system. Ultimately, the protein seizes and destroys that system, and HIV replicates.
But Oregon Health & Science University researchers who discovered the mechanism by which this destruction occurs say our innate protection system could have a leg up in the mêl
Could help improve treatment of anxiety
Behavior therapists may have a better way to help anxious patients, thanks to insights from a UCLA study of different ways to get mice past their fears. Rodents have long been used to study learning by association. Neuroscientists compared different ways of exposing mice to a stimulus that they had learned to fear, and found that “massing” the feared stimulus -– delivering it in concentrated bursts, not pacing it with longer pauses in between –
Could help improve treatment of anxiety
Behavior therapists may have a better way to help anxious patients, thanks to insights from a UCLA study of different ways to get mice past their fears. Rodents have long been used to study learning by association. Neuroscientists compared different ways of exposing mice to a stimulus that they had learned to fear, and found that “massing” the feared stimulus -– delivering it in concentrated bursts, not pacing it with longer pauses in between –