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The 35,000 or so genes within a human cell are something like players on a sports team: If their activity isn’t controlled and coordinated, the result can be disastrous.

So just as coaches tell individual players when to scramble onto the field and when to stay on the bench, molecules called transcription factors prompt particular genes to be active or stay quiet. Transcription factors occur naturally in cells, but researchers have been working to develop artificial transcriptio

For the first time in any animal, Duke University Medical Center researchers have linked a single pheromone receptor in the fruit fly to a specific sexual behavior.

Pheromones are chemical signals exuded by many animals — including humans — that serve as stimuli to evoke behavioral responses in other individuals of the same species. Pheromones often attract members of the opposite sex and provide important cues during courtship and mating.

Yet little is known about pheromone re

Physicists in the UK are ready to start construction of a major part of an advanced new experiment, designed to search for elusive gravitational waves. They are already part of two experiments: the UK/German GEO 600 project and the US LIGO experiment (Laser Interferometer Gravitational-Wave Observatory), both in their commissioning phases. By bringing GEO 600 technology to LIGO, they and their German colleagues from the Albert Einstein Institute are now set to become full partners in Advanced LIGO, a

By taking advantage of techniques developed in the search for Alzheimer’s treatments, a team of researchers has discovered that a molecule called Notch is essential for the development of critical kidney cells. The study, published online and in the Oct. 15 issue of the journal Development, provides key information about kidney development that could have implications for tissue regeneration.

“Tissue transplantation is fantastic but it would be so much better if we could instead raise o

Astronomers using NASA’s Hubble Space Telescope have discovered three of the faintest and smallest objects ever detected beyond Neptune. Each lump of ice and rock is roughly the size of Philadelphia and orbits just beyond Neptune and Pluto, where they may have rested since the formation of the solar system 4.5 billion years ago. The objects reside in a ring-shaped region called the Kuiper Belt, which houses a swarm of icy rocks that are leftover building blocks, or “planetesimals,” from the sola

More than 220 ideas for making European scientific endeavours and policies better known, understood and more attractive to the young and to the public at large are published today on the Web by the European Commission’s research and innovation information service CORDIS (www.cordis.lu/eoi/science-society/).

These ideas, initiated by citizens, public and private bodies, research and civil society organisations, as well as by the media, in 29 countries, represent the impressive results from a