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Making sense of the genome

Almost every week we hear of a new genome sequence being completed, yet turning sequence information into knowledge about what individual genes do is very difficult. An article published in Journal of Biology this week will simplify this task, as it describes a new online tool that dramatically improves predictions of how individual genes are regulated. Dr. Wyeth Wasserman and his team have created this powerful new two-step method for identifying which regulators of gene expression, called

Mouse study suggests mammoth evolutionary change

A study of a common wild mouse by two University of Illinois at Chicago biologists has found evidence of dramatic evolutionary change in a span of just 150 years, suggesting genetic evolution can occur a lot faster than many had thought possible.
The findings are the first report of such quick evolution in a mammal and appear in the May 22 issue of the journal Nature.

Oliver Pergams, a conservation biology researcher with the Chicago Zoological Society in Brookfield, Ill. and visiting

Getting through the matrix

MGH research suggests strategies for improving drug delivery to cancer cells

The best cancer drugs in the world are not much good if they cannot get to tumor cells. That problem has been challenging cancer physicians and researchers for years because the physical structure of many tumors can prevent anticancer agents from reaching their targets. In a study appearing in the June issue of Nature Medicine, researchers from Massachusetts General Hospital (MGH) describe a new technique for

Origin Of New Moons Explained

The ability to understand how small bodies such as moons switch from orbiting the Sun to orbiting a planet has long remained one of the outstanding problems of planetary science. A paper published in Nature on 15 May shows how this problem has been resolved using chaos theory, enabling scientists to predict where astronomers might search for new moons orbiting the giant planets.

In the last couple of years many small moons have been found orbiting the giant planets in our Solar System. For e

Researchers Develop Techniques for Computing Google-Style Web Rankingsup to Five Times Faster

Speed-up may make “topic-sensitive” page rankings feasible Computer science researchers at Stanford University have developed several new techniques that together may make it possible to calculate Web page rankings as used in the Google search engine up to five times faster. The speed-ups to Google’s method may make it realistic to calculate page rankings personalized for an individual’s interests or customized to a particular topic. The Stanford team includes grad

For best results, stick to one search engine

Web users who stick to one or two search engines and learn those well will have better results for their queries than users who try the same query or various engines, a Penn State researcher says.

“There are no wholesale rules about structuring a query that will work on multiple search engines,” said Bernard J. Jansen, assistant professor of information sciences and technology (IST). “And what works on one engine, such as narrowing a query, can have the opposite effect on other search engine

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