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OHSU researchers study smallpox vaccination protection over time

Scientists study those vaccinated more than 60 years ago versus one year ago

Oregon Health & Science University researchers are studying the effectiveness of the smallpox vaccine in patients who received inoculations decades ago compared with those vaccinated more recently. The universal belief has been that smallpox vaccinations provide protection for only three to five years. Until now scientists and physicians assumed that anyone vaccinated more than five years ago had little to n

New insights into how the nerve connection machinery remodels itself

A Duke University Medical Center neurobiologist has identified key mechanisms by which the intricate “protein machines” that govern the strength of connections among neurons build and remodel themselves to adjust those connections.

Such remodeling of the connections, called synapses, is central to the establishment of brain pathways during learning and memory, said the scientists. Also, malfunction of the synaptic machinery might well play a fundamental role in the pathology of neurodegenera

Computers worldwide speed search for anti-smallpox drugs

A major computer project has been launched today to analyse millions of different chemicals in the search for drugs to combat the bioterrorist threat of smallpox.

The smallpox research project will use the ‘screensaver downtime’ donated by up to two million computer users worldwide to screen 35 million compounds and identify those most likely to be suitable for drug development.

Currently no drugs are available to combat the smallpox virus after infection, and the only prevention i

Expendable microphones may help locate building collapse survivors

Data gathered by Penn State engineers in a volunteer effort at the World Trade Center tragedy, suggests that simple, inexpensive microphones dropped into the rubble of a collapsed building may be able to aid search and rescue teams despite ground level noise.

Dr. Thomas B. Gabrielson, associate professor of acoustics and senior research associate at Penn State’s Applied Research Laboratory, says, “In conventional survivor searches, noise generating activities at the surface must be stopped

Minimally invasive procedure fixes heart defect that allows blood clots to reach the brain

When 29-year-old Eric Lange suddenly experienced several hours of mental confusion last July, physicians at Cedars-Sinai Medical Center naturally ordered brain scans and carotid artery studies in their first search for a cause. With the initial exams turning out OK, Eric’s neurologist pursued other clues and ended up finding a heart defect called a patent foramen ovale, or PFO. A blood clot was believed to have slipped through the defect and out of the normal route of circulation that would

ESA on the trail of the earliest stars

Somewhere in the distant, old Universe, a population of stars hide undetected. They were the first to form after the birth of the Universe and are supposed to be far bigger in mass than any star visible today.

Astronomers know they must have been out there: only in this way could they solve the riddle of the origin and composition of stars in today’s Universe. A couple of ESA missions will help astronomers search for this elusive population.

When the Universe formed, there was

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