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Efficient processing and surface expression of tumor antigens are a prerequisite for successful immune-based cancer therapies. Unfortunately, spatial distribution of antigens is very difficult to determine with standard histological techniques. So cells might harbor tumor antigens inside the cytoplasm, but lack the appropriate MHC I or MHC II presentation on their cell surface. The current invention discloses a simple method to determine MHC-restricted presentation of any antigen of interest on the cell surface.
The new developed laser welding technology serves the parti-cle-free encapsulation of seal electronics against dust, humidity and gases.
The invention concerns a sensor for the magnetic field gradient and applies micromechanical structures. Lorentz-forces excite these structures whereas the vibrational modes are excited by the respective components of the magnetic gradient. This allows highly selective measurements of the respective gradient components. The invention was made by researchers of the Vienna University of Technology.
This technology is based on the combination of mid-IR ATR spectroscopy and the principle of ultrasonic particle Manipulation enabling the spatial control of said
particles.This technology is based on the combination of mid-IR ATR spectroscopy and the principle of
ultrasonic particle Manipulation enabling the spatial control of said particles.
Thermoplastic polyurethane elastomers (TPU) have segmented configuration consisting of macrodiol as flexible soft block, and a combination of diisocyante and chain extender as a rigid hard block. Advantages are suitable mechanics, biocompatibility and biodegradability.
The present invention relates to the use of Tyrosylprotein Sulfotransferase (TPST) and addresses the challenges of posttranslational modifications in plant-based protein expression systems by enabling human-type Protein sulfation in plants.