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Organic electronics with an edge

Using sophisticated theoretical tools, Agency for Science, Technology and Research (A*STAR) researchers, in Singapore, have identified a way to construct…

Molecular 'kiss of death' flags pathogens

Many bugs that make us sick — bacteria, viruses, fungi and parasites — hide out in our cells in protective little bubbles called vacuoles. To clear an…

Combined biogas upgrading & power-to-gas energy storage

The novel combined power-to-gas & Biogas upgrading Technology is producing high-purity methane, carbon dioxide and water in a single membrane separation system.

Coating of powder or fine grain particles by magnetron sputtering

Device and method to coat particles and powdres of any size and shape by magnetron sputtering. Even particles <1 μm can be coated and film thicknesses from 0.1 to 100 nm achieved. Use of metal or compound materials for adhesive, wear resistant, conductive and catalytic coatings.

Method for synthesizing therapeutic oligonucleotide conjugates with enhanced cellular uptake

A new and convenient synthesis method has been developed for coupling a ligand (e.g. PEG, peptides) through a cleavable disulfide linkage to an oligonucleotide at the 2´ position of a ribose ring. The resulting oligonucleotide conjugates are taken up efficiently into cells without the need for a transfection agent, and the 2´ OH group modification has
a positive impact on stability, allowing natural (phosphodiester) oligonucleotide sequences to be used. Preliminary in vitro experiments have demonstrated effective target gene down-regulation.

Synthetic lignans targeting cardiovascular diseases

Novel synthetic lignans to affect inflammatory processes related to surgical cardiovascular intervention have been identified. The compounds may have highly beneficial effects for preparation of cardiac by-pass implants as well as for stent conduits.

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