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If someone has sustained a life-threatening brain injury, for example, they often need to be transferred to a specialist hospital. This hospital receives the…

Bei der vorliegenden Erfindung handelt es sich um ein Verfahren zur Herstellung dünner Polymer-Elektrolyte, die zudem mechanisch stabil und gleichzeitig auch flexibel sind. Diese zeichnen sich durch gute ionische Transporteigenschaften aus, d.h. die Leitfähigkeit bei Raumtemperatur beträgt 1 mS/cm. Die Membranen können aufgrund ihrer mechanischen Eigenschaften in Lithium-basierten Energiespeichen gleichzeitig als Elektrolyt und Separator eingesetzt werden. Das Verfahren ermöglicht die Verarbeitung von Polyacrylnitril basierten Membranen zusammen mit dem Lithiumleitsalz und ermöglicht eine gleichmäßige Materialstärke.

The invention consists of a cooled cylinder unit for a rheometer
and a method to identify rheological properties. By use of the
invention the cooling time in convective cooled rheometers can be
reduced. This can be necessary to reduce or prevent thermal
degradation of thermal sensitive polymers (i.e. biobased or bio-
degradable polymers).

A team of highly determined high school students discovered a never-before-seen pulsar by painstakingly analyzing data from the National Science Foundation's…

Its efficiency and methodological rigour has now led the algorithm to be incorporated in the world’s most widely-used DNA-analysis software. This momentous…

Injury results in release of cytoplasmic ATP, which is sensed by monocytes/macrophages via ATP receptor P2X7. This swiftly induces inflammasome activation, caspase-1-dependent cleavage and release of interleukin-1ß (IL-1ß), IL-18 and HMGB1. Excessive systemic IL-1ß release is the first stage of a reaction chain causing SIRS and high patient mortality.

IL-1ß is involved in host defense against infections. Pathogen-induced inflammasome activation, however, typically involve ATP-independent pathways. Hence, a-1-antitrypsin, SLPI, CRP, and DPPC inhibit injury induced inflammation but do not inhibit clearance of pathogens.

Scope of application: SIRS, Major surgery, Trauma, Extracorporeal circulation (e.g. cardiopulmonary bypass, ECMO), Chronic inflammation, Lung injury

SIRS-related multi organ dysfunction (MODS) and acute lung injury (ALI) are among the leading causes of death worldwide. The proposed remedies have the potential to become affordable life-saving medicaments for numerous indications.