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Researchers at the Karlsruhe Institute of Technology (KIT) have successfully developed low-cost, fluorescent dyes with especially high light intensities. These inorganic–organic hybrid dyes can be synthesized easily and isolated, stored and redispersed in common solvents (ethanol/water). They can be excited using blue light (UV or blue light from LED) and emit depending on their composition in the blue, green, red or infrared spectrum. Preferred are applications in the field of medical diagnostic and therapeutic, advertising material and safety equipment (fluorescent marker).
At present about 18 million people worldwide suffer from Alzheimer disease, a neurodegenerative disorder which leads to dementia. The pharmaceuticals currently registered for the treatment of Alzheimer are only able to reduce symptoms marginally and delay progression of Alzheimer disease to a limited extent. The novel preventive target structure, the APP-AICD/ Fe65-PTB2 complex, offers a new chance for the development of a possible pharmaceutical for a causal treatment of Alzheimer disease.
The invention concerns a surgical drape, especially for surgical interventions on the brain or head.
These novel drapes are provided to cover two areas. First the sterile cover of the area of surgery and additionally the sterile cover for a surveying system, especially with infrared radiation.
Previous drapes, especially for surgeries on the brain or head have only one fenestration in the area under the contact area of the patients head.
The tin-enriched adhesive system according to the invention provides a better and more durable bonding of tooth-colored filling materials (composites/ceramics) to eroded hard tooth substance. This system was specifically designed for individuals with pre-eroded teeth, can however also be used for all other indications of tooth-colored restorations.
This invention offers a new method for the direct and halogen-free formamide or acetamide formation of adamantane.
The adamantane modifications are chosen to enhance lipophilicity and stability of drugs, thereby improving their pharmacokinetics. Amido- and amino admantane derivatives can be used as drug delivery systems. They are able to overcome the blood-brain barrier and are competent to penetrate into the fatty tissue.
Due to these properties adamantane derivates are already used as therapeutics (e.g. for neurodegenerative diseases) and cosmetics. They are, for example, used as antiviral drugs or to treat Parkinson?s as well as Alzheimer?s diseases.
Not in all cases where nature and biodiversity conservation is intended, species protection is the outcome. The ambitious political target e.g. of the German…