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Researchers from the National University of Singapore (NUS) have discovered a new reproductive mode in frogs and toads – breeding and laying direct developing…
Chinese Hamster ovary (CHO) cells are commonly used as a mammalian expression system for the production of recombinant proteins. They are one of the few cell types that can be grown at high cell density as the cells are resistant to metabolic stress. However, given the considerable production costs it is of major importance to maximize the recombinant protein yield. The present invention allows for significantly increasing the recombinant protein expression level in CHO cells using a standard promoter. This is achieved by silencing the Galectin-1 gene through RNAi. The lentiviral Galectin-1-knockdown (>90%) increases the expression level of the protein of interest more than 1,5-fold. No further amendments are required.
The invention concerns a process for the production of bifurcated vascular prostheses by the polymer-processing technology electrospinning.
The development of a new organism from the joining of two single cells is a carefully orchestrated endeavor. But even before sperm meets egg, an equally…
The roadmap focuses on strategic and tactical objectives to support the federal government's accelerated adoption of cloud computing. This final document…
The present innovation provides stable aqueous suspensions of water-insoluble, but biodegradable diblock copolyesters which can be further processed in multiple ways, for instance via electrospinning.