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Beta lactones are synthetically produced small molecules that tremendously reduce the pathogenicity of Staphylococcus aureus and MRSA. They act by inhibiting the caseinolytic protease P (ClpP), a key regulator of multiple virulence factors. Thereby the production of detrimental bacterial toxins (i.e. hemolysins, toxic shock syndrome toxin, enterotoxins) is prevented resulting in disarming the bacteria during infection. Bacterial killing and clearance can therefore be achieved through the action of the immune system.
Importantly, the concept of antivirulence prevents both the biggest challenges in antibiotic treatment today: resistance development and side effects. This also allows for longer treatment periods.
A newly developed method for water treatment makes it possible to reduce costs of investment as well as energy consumption of conventional seawater desalination plants. The method comprises an innovative, environment-friendly und energy efficient solution, which is suitable for desalination as well as for process water treatment from oil or gas industry, mining, electroplating, food industry and Zero Liquid Discharge – ZLD.
The ARMC5 gene was discovered by independent workgroups studying benign tumours – so-called adrenal adenomas – in connection with Cushing’s syndrome. In this…
Tailored to the current practical requirements, the FoBt Sensor has been developed by the Institute of Nanotechnologies and Optical Technologies (iNano) at the Niederrhein University of Applied Science. Persistent and unrecognized moisture lead to moisture damage and loss of quality on different kinds of products. The novel optical fiber sensor (FoBt Sensor) from iNano combines the detection of water condensation on the probe tip surface with an active determination of the condensation rate and the temperature measurement at the sensor head. This is made possible through the application of the optical fiber sensor principle and the special design of the probe tip.
Science in clear words: Dr. Sebastian Trimpe, a research scientist in the “Autonomous Motion Department” (Stefan Schaal) at the Tübingen Max Planck Institute…
“While laboratory studies support an important role for cholesterol in prostate cancer, population-based evidence linking cholesterol and prostate cancer is…