According to current estimates, there are more than 200 million people worldwide suffering from malaria, and roughly one million die each year from this…
Liquid water is an essential ingredient for life as we know it. Mars is one of the very few places in the solar system where scientists have seen promising…
A German-Chinese research team has discovered a wasp with a unique nest-building strategy in the forests of southeast China:
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the third most common cause of cancer related death worldwide. Cure of HCC is only possible by complete resection in early stages, but only 1020% of tumors can be curatively resected and the risk of HCC recurrence is high. In addition, HCC is resistant to conventional radio- or chemotherapy. As a result, the prognosis of HCC remains poor and new therapies are urgently needed. The discovery of so far unknown immunodominant epitopes of the tumor-associated antigen Glypican-3 and the according HLA-A2 restricted T-cell-receptor enable the development of an adoptive T cell therapy for HCC patients. Adoptive T cell therapies showed very promising results in cancer therapy over the last years. The Science Magazine even awarded this technology as Breakthrough of the year 2013. Therefore, the current invention provides the tools for a promising new approach for the therapy of HCC.
Nachhaltigkeit spielt nicht nur in der Klimaforschung oder für die Energiegewinnung eine Rolle, sondern beispielsweise auch in Sport, Gesundheit oder…
Sodium channels and calcium channels are molecular portals that allow controlled passage of ions across a cell’s membrane; they are required for healthy brain,…